MULTIMETHOD ASSESSMENT OF DRIVING SKILLS IN ADHD TEENS

多动症青少年驾驶技能的多方法评估

• 批准号: 6266361
• 负责人: RUSSELL A BARKLEY
• 金额: $ 32.22万
• 依托单位: UNIV OF MASSACHUSETTS MED SCH WORCESTER
• 依托单位国家: 美国
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-05-01 至 2002-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6266361
• 关键词: accident proneness; adolescence (12-20); amphetamines; attention deficit disorder; behavior prediction; behavior test; behavioral /social science research tag; computer simulation; driving while intoxicated; drug interactions; ethanol; human subject; legal /correctional; mental disorder chemotherapy; patient oriented research; psychomotor function; psychopharmacology; vehicular accident

DESCRIPTION: Past research has suggested that teens and young adults with attention deficit hyperactivity disorder (ADHD) may be at greater risk than normal peers for traffic offenses, driving while intoxicated, motor vehicle crashes, and license suspensions and revocations. The original phase of the project undertook a multi-source, multi-level, and multi-method assessment of driving competence, knowledge, decision-making, and adverse outcomes in a large sample of both ADHD (N=105) and control (N=64) teens and young adults. Numerous deficits in basic psychological abilities subserving driving, driving behavior, driving simulator performance, and driver knowledge and rapid decision-making were identified in the ADHD group. Using both self-reports and official DMV records, our study also supported earlier research on the greater citation and accident risks associated with ADHD. Severity of ADHD symptoms and frequency of alcohol use and drunkenness were among the best predictors of citation and crash risks. The present application is a two-year competing renewal designed to extend the investigators' research on driving risks to the next logical step by addressing two important questions: 1) Can these driving deficiencies and related risks associated with ADFID be effectively treated with stimulant medication?; and 2) does the use of alcohol before driving produce a differentially greater adverse impact on driving performance in ADHD than in normal peers? Two studies are proposed to address these issues. Study I will use a within subjects reversal design to examine the efficacy of two doses of Adderall (5mg and 10mg) and a placebo on 90 ADFID teens/young adults using a multi-method multi-level battery of driving measures including a new, state-of-the-art driving simulator not available to our prior project. Study II will compare 78 ADFID and 78 control young adults using a within-groups design for the effects of two different doses of alcohol and a placebo on driving performance using the same assessment battery. Results will have substantial clinical import concerning possible effective treatments for driving risks in ADHD youth and the adverse impact of alcohol consumption on driving in ADHD young adults.

描述：过去的研究表明，青少年和患有 注意缺陷多动障碍(ADHD)的风险可能比 交通肇事、酒后驾车、机动车的正常同伴 车祸，以及吊销和吊销执照。的原始阶段 项目进行了多源、多层次、多方法的评估 推动能力、知识、决策和不良后果 ADHD(N=105)和对照组(N=)青少年和青壮年样本。数不胜数 为驾驶、驾驶行为服务的基本心理能力缺陷， 驾驶模拟器性能、驾驶员知识和快速决策 在ADHD组中被发现。使用自我报告和官方车管所 记录，我们的研究也支持了早期关于更大引文和 与ADHD相关的事故风险。ADHD症状的严重程度和频率 酒精使用和醉酒是最好的引证和 撞车风险。本申请是一项为期两年的竞争性续订计划 将调查人员对驾驶风险的研究扩展到下一个合乎逻辑的步骤 通过解决两个重要问题：1)这些驾驶缺陷和 与ADFID相关的风险可用兴奋剂有效治疗 药物治疗？以及2)开车前饮酒是否会产生 ADHD患者对驾驶性能的不利影响比 正常同龄人？提出了两项研究来解决这些问题。我会好好学习的 使用受试者内反转设计来检查两种剂量的 阿得拉(5 mg和10 mg)和安慰剂对90名ADFID青少年/年轻人使用 多方法多电平蓄电池的驱动措施包括新的， 最先进的驾驶模拟器不适用于我们之前的项目。研究报告II 将使用组内设计对78名ADFID和78名对照年轻人进行比较 两种不同剂量的酒精和安慰剂对驾驶的影响 使用相同评估电池的性能。结果将会有实质性的 关于驾驶风险的可能有效治疗的临床导入 ADHD青少年与饮酒对ADHD驾驶的不良影响 年轻人。