ONTOGENY & FUNCTION OF PRIMATE VOCALIZATIONS

个体发育

• 批准号: 6311805
• 负责人: HAROLD T. GOUZOULES
• 金额: $ 3.85万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1976
• 资助国家: 美国
• 起止时间: 1976-06-01 至 2001-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6311805
• 关键词: Mammalia; behavioral /social science research tag; congenital disorders; eye; growth /development; nervous system; psychology; vision

The overall goal of this project is to discover better ways to prevent and treat conditions that lead to blinding disorders in human children. We focus on neural and behavioral abnormalities associated with conditions such as congenital cataracts that occur during the neonatal period. During the past year we have continued to study abnormalities in motion processing, oculomotor behavior, and regulation of eye growth that occur following neonatal visual deprivation, but not during visual deprivation initiated somewhat later during postnatal development. These include abnormal growth of the eye leading to anisometropia, and asymmetrical responses to horizontal motion as assessed with visually evoked potentials and oculomotor measures. Monkeys reared under conditions of neonatal visual deprivation in previous years continue to be studied for the long-term presence of all of these disorders. Five new animals were reared under conditions of restricted binocular expo sure duri ng the past year, and those infants will be tested with ophthalmological, electrophysiological, psychophysical, and oculomotor methods during the coming year. FUNDING NIH EY05975 $166,645 7/1/95 - 6/30/00 PUBLICATIONS Boothe, R.G. and Fulton, A.B. Amblyopia. In Principles and Practice of Ophthalmology, 2nd Edition, D.M. Albert and F.A. Jakobiec (Eds.), W.B. Saunders Company, (In press). Bradley, D.V., Fernandes, A., Lynn, M., Tigges, M. and Boothe, R.G. Emmetropization in the rhesus monkey (Macaca mulatta) Birth to young adulthood. Invest. Ophthalmol. Vis. Sci. (In press). Bradley, D.V., Fernandes, A. and Boothe, R.G. The refractive development of untreated eyes of rhesus monkeys varies according to the treatment received by their fellow eyes. Vision Res. (In press). Brown, R.J., Wilson, J.R., Norcia, A.M. and Boothe, R.G. Development of directional motion symmetry in the monocular visually evoked potential of infant monkeys. Vision Res. 38:1253-1263, 1998. Wilson, J.R., Noyd, W.W., Aiyer, A.D., Norcia, A.M., Mustari, M.J. and Boothe, R.G. Asymmetric responses in cortical visually evoked potentials to motion are not derived from eye movements. Invest. Ophthalmol. Vis. Sci. (In press). P51RR00165-38 1/1/98 - 12/31/98 Yerkes Regional Primate Research Center

该项目的总体目标是发现更好的方法 预防和治疗导致人类失明的疾病 孩子们。 我们专注于相关的神经和行为异常 患有先天性白内障等疾病 新生儿期。 在过去的一年里，我们不断学习 运动处理、动眼神经行为异常 新生儿视觉后眼睛生长的调节 剥夺，但不是在视觉剥夺期间开始的 后来在产后发育期间。 这些包括异常生长 眼睛导致屈光参差和不对称反应 通过视觉诱发电位评估水平运动和 动眼神经措施。 在新生儿条件下饲养的猴子 前几年的视觉剥夺继续进行研究 所有这些疾病的长期存在。 五种新动物 在限制双眼曝光的条件下饲养 去年，这些婴儿将接受眼科检查， 电生理学、心理物理学和动眼神经学方法 来年。 资金 NIH EY05975 $166,645 7/1/95 - 6/30/00 出版物 Boothe, R.G.和富尔顿，A.B.弱视。 原则上 眼科与实践，第二版，D.M.艾伯特和 F.A. Jakobiec（编辑），W.B.桑德斯公司，（正在印刷中）。 布拉德利，D.V.， Fernandes, A.、Lynn, M.、Tigges, M. 和 Boothe, R.G.正视化 在恒河猴（Macaca mulatta）出生到成年早期。 投资。 眼药水。 维斯。科学。 （正在印刷中）。 布拉德利，D.V.，费尔南德斯， A. 和布斯，R.G.未经治疗的眼睛的屈光发育 恒河猴根据其接受的治疗而有所不同 同胞的眼睛。 视觉研究中心。 （正在印刷中）。 布朗，R.J.，威尔逊，J.R.， 诺尔恰，A.M.和布斯，R.G.定向运动的发展 幼猴单眼视觉诱发电位的对称性。 视觉研究中心。 38：1253-1263，1998。威尔逊，J.R.，诺伊德，W.W.，​​艾耶尔， A.D.、Norcia, A.M.、Mustarari, M.J. 和 Boothe, R.G.不对称 皮层视觉诱发电位对运动的反应不是 源自眼球运动。 投资。 眼药水。 维斯。科学。 （在 按）。 P51RR00165-38 1/1/98 - 12/31/98 耶克斯地区灵长类动物 研究中心