CORE--LABORATORY

该核心为所有项目提供服务。它提供给博士。 Reids的时间用于整体计划项目管理，与 项目和数据处理，以及协助核心。博士 Shankar将是核心的现场总监，负责所有 出现的地方问题。 核心人员负责确保 临床数字化仪和来自托马斯临床核心（A）的数据传输 杰斐逊大学医院的调查人员在德雷克塞尔和在 肯塔基州大学。核心B人员还负责 协助所有项目接收数据并将其转换为 格式.他们购买或建造特殊的仿组织幻影 任何项目都需要。 核心包含一个计算机控制的扫描仪，用于制作B模式图像 从德雷塞尔实验室获得的动物组织 大学动物设施。新单元件的初步测试 项目7的传感器将由该设施制造。 核心位于生物医学工程学院，科学与 德雷克塞尔大学的健康系统，并方便所有的 德雷克塞尔的调查员。临床中心的光盘 从托马斯杰斐逊大学医院乘地铁到实验室， 15分钟车程。一旦检查，这些数据将 所有研究者（包括肯塔基州的Donohue博士）可通过 德雷克塞尔以太网 核心设施由主要研究者分配。的建议 将设立一个项目领导人小组来解决冲突。 组织定征方法的成功将通过以下方式进行评价： 使用病理结果进行ROC分析。ROC的进一步发展 方法将进行评估我们的超声波的疗效 诊断方法。

This core provides services to all of the projects. It provides for Dr. Reids' time for overall Program Project management, consultations with the projects and data handling, as well as for assisting with the core. Dr. Shankar will be the on-site director of the Core, responsible for all of the local matters that arise. The core personnel are responsible for assuring proper operation of the clinical digitizer and data transfer from the Clinical Core (A) at Thomas Jefferson University Hospital to investigators at Drexel and at the University of Kentucky. Core B personnel are also responsible for assisting all projects in receiving and translating data into their formats. They purchase or construct special tissue-mimicking phantoms as needed in any project. The core contains a computer-controlled scanner for making B mode images of phantoms and of animal tissues to be obtained from the Drexel University animal facility. Initial tests of new single-element transducers from project 7 will be made by this facility. The core is located in the School of Biomedical Engineering, Science and Health Systems of Drexel University, and is convenient to all of the Drexel investigators. The optical discs from the Clinical Core are brought to the laboratory by subway from Thomas Jefferson University Hospital, which ia a 15 minute ride away. Once checked, these data are made available to all investigators (including Dr. Donohue at Kentucky) through the Drexel ethernet. Core facilities are assigned by the Principal Investigator. The advice of a panel of the Project Leaders will be sought to resolve conflicts. The success of the tissue characterization methods will be evaluated by ROC analysis using results of pathology. Additional development of ROC methods will be undertaken to evaluate the efficacy of our ultrasonic methods in diagnosis.