A novel strategy to enhance T cell-mediated immunity to vaccine antigens

增强 T 细胞介导的疫苗抗原免疫的新策略

• 批准号: nhmrc : 1000703
• 负责人: A/Pr Charani Ranasinghe
• 金额: $ 15.64万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Development Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/novel-strategy-enhance-vaccine-antigens/99480
• 关键词: novel; strategy; enhance; cell; mediated

Globally there are about 33 million people living with HIV. The disease has already resulted in 23 million deaths and 2.5 million people are newly infected each year. Similarly, TB kills nearly 2 million people every year and infects about 1% of the worldÍs population every year. A vaccine is the best and also likely the only long-term solution for HIV/TB disease prevention. This research proposal looks at novel strategies to increase the efficacy of vaccines for diseases such as HIV/TB.

全球约有3300万人感染艾滋病毒。该疾病已造成2300万人死亡，每年有250万人新感染。同样，结核病每年导致近200万人死亡，每年感染约1%的worldÍs人口。疫苗是预防艾滋病毒/结核病的最佳，也可能是唯一的长期解决方案。这项研究建议着眼于提高艾滋病毒/结核病等疾病疫苗效力的新策略。