RES FACIL CONST: RHESUS MODEL, STEM CELLS

RES FACIL CONST：恒河猴模型，干细胞

• 批准号: 6794465
• 负责人: PETER Ogden KOHLER
• 金额: $ 35.6万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-15 至 2003-09-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794465
• 关键词: Macaca mulatta; animal colony; biological models; biomedical facility; building /facility design /renovation; disease /disorder model; stem cells; university

DESCRIPTION (provided by applicant): This application requests funds to construct Phase II infill to the Animal Services Building (ASB) addition that will provide housing for 544 non-human primates (NHPs) in an 11,970 sq. ft. state-of-the art facility. The expansion will enable the Oregon Regional Primate Research Center (ORPRC) to meet rapidly growing research needs, as well as comply with new United States Department of Agriculture (USDA) mandated standards for expanded social housing. The Oregon Health and Science University (OHSU) made a major commitment by providing approximately $4 million in funds to construct a 35,600 sq. ft. shell addition to the ASB. Phase I infill consists of a 13,000 sq. ft. facility that will house up to 192 NHPs, as well as provide behavioral testing rooms, and office and new cage wash areas. Rapid growth in various research areas necessitates additional NHP housing. Current NHP housing is full, resulting in the following problems: 1) limited ability to meet the needs of existing research programs or begin new projects; 2) delayed procurement of needed animals; 3) delayed renovations due to lack of flex space; and 4) delayed implementation of social housing. The Specific Aims of this application are to construct Phase II infill of the ASB addition, consisting of Animal Biosafety Level 2 (ABL2) containment housing for up to 544 NHPs in 17 animal holding rooms, a feed storage room and a procedure room. Each animal holding room will contain 32 NHPs in paired cages, as well as large group play enclosures to permit groups of animals to regularly experience an enhanced social environment.

描述（由申请人提供）：本申请要求资金用于建造动物服务大楼 (ASB) 扩建项目的第二期填充工程，该大楼将为 544 只非人类灵长类动物 (NHP) 在 11,970 平方英尺的最先进设施中提供住房。此次扩建将使俄勒冈地区灵长类动物研究中心 (ORPRC) 能够满足快速增长的研究需求，并符合美国农业部 (USDA) 扩大社会住房的新规定标准。俄勒冈健康与科学大学 (OHSU) 作出重大承诺，提供约 400 万美元的资金，为 ASB 建造 35,600 平方英尺的外壳。第一阶段的填充包括一个 13,000 平方英尺的设施，将容纳多达 192 个 NHP，并提供行为测试室、办公室和新的笼子清洗区。 各个研究领域的快速发展需要额外的 NHP 住房。目前NHP住房已满，导致以下问题：1）满足现有研究计划或开始新项目需求的能力有限； 2）延迟采购所需动物； 3）由于缺乏弹性空间而推迟装修； 4）社会住房的延迟实施。该应用的具体目标是建造 ASB 附加设施的第二期填充，包括动物生物安全 2 级 (ABL2) 收容室，可容纳 17 个动物储藏室、一个饲料储藏室和一个手术室，最多可容纳 544 个 NHP。每个动物饲养室将在成对的笼子中容纳 32 个 NHP，以及大型团体游戏围栏，让动物群体定期体验更好的社交环境。