RES FACIL CONST: RHESUS MODEL, OBESE

RES FACIL CONST：恒河猴模型，肥胖

• 批准号: 6794462
• 负责人: PETER Ogden KOHLER
• 金额: $ 35.6万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-15 至 2003-09-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794462
• 关键词: Macaca mulatta; animal colony; biological models; biomedical facility; building /facility design /renovation; disease /disorder model; obesity; university

DESCRIPTION (provided by applicant): This application requests funds to construct Phase II infill to the Animal Services Building (ASB) addition that will provide housing for 544 non-human primates (NHPs) in an 11,970 sq. ft. state-of-the art facility. The expansion will enable the Oregon Regional Primate Research Center (ORPRC) to meet rapidly growing research needs, as well as comply with new United States Department of Agriculture (USDA) mandated standards for expanded social housing. The Oregon Health and Science University (OHSU) made a major commitment by providing approximately $4 million in funds to construct a 35,600 sq. ft. shell addition to the ASB. Phase I infill consists of a 13,000 sq. ft. facility that will house up to 192 NHPs, as well as provide behavioral testing rooms, and office and new cage wash areas. Rapid growth in various research areas necessitates additional NHP housing. Current NHP housing is full, resulting in the following problems: 1) limited ability to meet the needs of existing research programs or begin new projects; 2) delayed procurement of needed animals; 3) delayed renovations due to lack of flex space; and 4) delayed implementation of social housing. The Specific Aims of this application are to construct Phase II infill of the ASB addition, consisting of Animal Biosafety Level 2 (ABL2) containment housing for up to 544 NHPs in 17 animal holding rooms, a feed storage room and a procedure room. Each animal holding room will contain 32 NHPs in paired cages, as well as large group play enclosures to permit groups of animals to regularly experience an enhanced social environment.

描述（由申请人提供）：本申请要求提供资金，用于建造动物服务大楼（ASB）的第二阶段填充物，该大楼将为544只非人灵长类动物（NHP）提供11，970平方英尺的住房。英尺最先进的设备此次扩建将使俄勒冈州区域灵长类动物研究中心（ORPRC）能够满足快速增长的研究需求，并遵守美国农业部（USDA）关于扩建社会住房的新强制标准。俄勒冈州健康与科学大学（OHSU）作出了重大承诺，提供约400万美元的资金，建造一个35，600平方米。英尺添加到ASB的shell。第一阶段填充物包括13，000平方米。英尺该设施将容纳多达192名NHP，并提供行为测试室，办公室和新的笼子清洗区。 各种研究领域的快速增长需要更多的NHP住房。目前的NHP住房已满，导致以下问题：1）满足现有研究计划或开始新项目需求的能力有限; 2）所需动物的采购延迟; 3）由于缺乏灵活空间而延迟翻修;以及4）延迟实施社会住房。本申请的具体目的是构建ASB添加物的第II阶段填充物，包括动物生物安全2级（ABL 2）防护罩，可容纳17个动物饲养室、饲料储存室和手术室中的544名NHP。每个动物饲养室将在成对的笼子里包含32个NHP，以及大型群体游戏围栏，以允许动物群体定期体验增强的社会环境。