IMPROV OF RES FACIL: NUTRITION, SOY-BASED COMP

改善资源设施：营养、大豆成分

• 批准号: 6794365
• 负责人: PETER LANGE
• 金额: $ 40万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-06-01 至 2003-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794365
• 关键词: animal colony; biomedical facility; brain; building /facility design /renovation; laboratory mouse; neurogenetics; neuropsychology; nutrition

DESCRIPTION (provided by applicant): The long-term objective of the proposed project is to create a unique, state-of-the-art facility for behavioral neuroscience and genomics research, to be called the Center for Behavioral Neuroscience and Genomics, within Duke's Center for Models of Human Disease. This facility will unite behavioral neuroscientists with cell and molecular biologists to investigate the brain and behavioral mechanisms underlying cognitive and motivational systems. Specific Aims: 1) bring behavioral neuroscientists in close proximity to cell biologists and geneticists so that they can join forces to seek molecular mechanisms underlying adaptive behaviors; 2) provide a facility with modular units that are easily adaptable to current and future research needs; 3) offer common research resources that can be readily used by all researchers in the facility and by collaborators; 4) create common infrastructure resources so that space is used maximally and efficiently; 5) provide expanded animal housing - 1,000 rat cages, 100 mouse rages, and 100 other types (e.g., birds, fish) - that will more than double current capacity, markedly enhancing long-term animal housing; and 6) establish a clear separation of animal research and public space so that security, noise, and air-handling can be tightly controlled and monitored, which is essential for high quality behavioral research.

描述（由申请人提供）：拟议项目的长期目标是在杜克人类疾病模型中心内创建一个独特的、最先进的行为神经科学和基因组学研究设施，称为行为神经科学和基因组学中心。该设施将联合行为神经科学家与细胞和分子生物学家研究认知和动机系统的大脑和行为机制。 具体目标：1）使行为神经科学家与细胞生物学家和遗传学家紧密联系，以便他们能够联合起来寻找适应性行为背后的分子机制; 2）提供具有易于适应当前和未来研究需求的模块化单元的设施; 3）提供可以由设施中的所有研究人员和合作者随时使用的共同研究资源; 4）创建公共基础设施资源，以便最大限度地有效利用空间; 5）提供扩大的动物住房- 1,000个鼠笼，100个鼠笼和100个其他类型（例如，鸟类，鱼类）-这将增加一倍以上的电流容量，显着提高长期的动物住房;和6）建立一个明确的动物研究和公共空间的分离，使安全，噪音和空气处理可以严格控制和监测，这是必不可少的高质量的行为研究。