CONST OF VACCINE CTR: AUTOIMMUN

疫苗 CTR 的稳定性：自身免疫

• 批准号: 6794426
• 负责人: Alexander H. Lucas
• 金额: $ 40万
• 依托单位: CHILDREN'S HOSPITAL & RES CTR AT OAKLAND
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-05-01 至 2003-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794426
• 关键词: autoimmunity; biomedical facility; building /facility design /renovation; communicable diseases; immunology; polymerase chain reaction; training; vaccine development

DESCRIPTION (provided by applicant): This application seeks funds from the National Center for Research Resources (NCRR) to support construction of the CIVD being established at the CHORI. The Center will consist of new laboratories, core facilities and office spaces suitable to house the research, research training and research support activities of several integrated scientific programs. The investigators who will occupy the Center conduct molecular, cellular and clinical studies in the inter-related areas of immunobiology, infectious diseases, pathogenesis, vaccine development and vaccine evaluation. As a group, the CIVD investigators have 18 extramural awards with total direct costs in year 2001 that exceed $3 million of which 75 percent derives from the National Institutes of Health (NIH). Dr. Dan Granoff will be the Scientific Director of the Center. Dr. Alexander Lucas, Deputy Director of Medical Research at CHORI, is the Principal Investigator (PI) and will be responsible for the space utilization and the administrative management of the Center. CHORI has made a substantial financial commitment to this project and has designated the CIVD as a high priority in its Strategic Plan. Approximately 8,000 sq. ft. of undeveloped shell space will be used for construction of the CIVD. The Center will provide interactive laboratory and office spaces as well as specialized shared core facilities, such as a Biosafety Level 3 (BSL3) facility and a DNA clean room for polymerase chain reaction (PCR) assembly. Construction of the CIVD will expand investigators' research capabilities, promote programmatic interaction and growth, increase training opportunities, and permit recruitment of additional scientists.

描述（由申请人提供）：本申请寻求国家研究资源中心（NCRR）的资金，以支持在合唱团建立的CIVD的建设。该中心将包括适合在几个综合科学计划的研究，研究培训和研究支持活动的新实验室，核心设施和办公空间组成。将占用该中心的研究人员在免疫生物学，传染病，发病机理，疫苗发育和疫苗评估的相关区域进行分子，细胞和临床研究。作为一个小组，CIVD调查人员获得了18年的18年直接成本，其总成本超过300万美元，其中75％来自美国国立卫生研究院（NIH）。 Dan Granoff博士将担任该中心的科学主任。 Chori医学研究副主任Alexander Lucas博士是首席研究员（PI），将负责该中心的太空利用率和行政管理。 Chori对该项目做出了实质性的财务承诺，并将CIVD指定为其战略计划中的重中之重。大约8,000平方英尺的未开发壳空间将用于建造CIVD。该中心将提供交互式实验室和办公空间以及专门的共享核心设施，例如生物安全3级（BSL3）设施和用于聚合酶链反应（PCR）组件的DNA清洁室。 CIVD的建设将扩大研究人员的研究能力，促进程序化互动和增长，增加培训机会，并允许招募其他科学家。