Effect of Renal Insufficiency on Cardiovascular Outcomes
Effect of Renal Insufficiency on Cardiovascular Outcomes
批准号:
6326540
负责人:
STEVE J SCHWAB
金额:
$31.19万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-06-15 至 2003-05-31
中文摘要
描述(从应用程序逐字):心血管疾病帐户
英文摘要
DESCRIPTION (Verbatim from the application): Cardiovascular disease accounts
for almost half of the reported deaths for patients receiving maintenance
dialysis. Because incident dialysis patients often have advanced coronary
artery disease that is less amenable to treatment as compared with patients
with normal renal function, the greatest impact of therapy will be obtained
through invention among patients with renal insufficiency, prior to their
development of ESRD and earlier in the development of the coronary artery
lesions. This proposal will define the impact of varying degrees of chronic
renal insufficiency on five-year survival among patients with significant
coronary artery disease. This study will further compare patient survival
following treatment for coronary artery disease (medical, percutaneous coronary
artery intervention and coronary artery bypass grafting) among patients with
mild, moderate, and severe renal insufficiency. After evaluating these clinical
outcomes, this proposal will estimate the cumulative five-year medical resource
utilization (rehospitalizations and cardiac procedures) and costs for patients
with chronic renal insufficiency and significant coronary artery disease to
compare costs among major patient subgroups. A retrospective cohort design will
be used to take advantage of the Duke Databank for Cardiovascular Diseases
(DDCD), a large, comprehensive patient database, maintained by the Duke
Clinical Research Institute (DCRI) and its associated hospital and physician
administrative databases. This study will examine the cardiovascular outcomes
that affect the survival of patients with chronic renal insufficiency and
patients receiving chronic dialysis. The results of this study will provide
evidence for early intervention among the pre-ESRD population with chronic
renal insufficiency to improve maximize the efficacy of coronary
revascularization and improve survival.
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Effect of Renal Insufficiency on Cardiovascular Outcomes
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批准号:6601135
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项目类别:
-
资助金额:$2.9万
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财政年份:2001
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负责人:STEVE J SCHWAB
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依托单位:
HEMODIALYSIS VASCULAR ACCESS CLINICAL TRIALS CONSORTIUM
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批准号:6381968
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项目类别:
-
资助金额:$27.49万
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财政年份:2000
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负责人:STEVE J SCHWAB
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依托单位:
HEMODIALYSIS VASCULAR ACCESS CLINICAL TRIALS CONSORTIUM
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批准号:6291558
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项目类别:
-
资助金额:$27.49万
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财政年份:2000
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负责人:STEVE J SCHWAB
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依托单位:
MORBIDITY AND MORTALITY IN HEMODIALYSIS PATIENTS
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批准号:2518436
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项目类别:
-
资助金额:$23.82万
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财政年份:1994
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负责人:STEVE J SCHWAB
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依托单位:
MORBIDITY AND MORTALITY IN HEMODIALYSIS PATIENTS
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批准号:2149911
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项目类别:
-
资助金额:$19.3万
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财政年份:1994
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负责人:STEVE J SCHWAB
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依托单位:
MORBIDITY AND MORTALITY IN HEMODIALYSIS PATIENTS
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批准号:2149910
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项目类别:
-
资助金额:$21.16万
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财政年份:1994
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负责人:STEVE J SCHWAB
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依托单位:
MORBIDITY AND MORTALITY IN HEMODIALYSIS PATIENTS
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批准号:2905710
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项目类别:
-
资助金额:$23.55万
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财政年份:1994
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负责人:STEVE J SCHWAB
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依托单位:
MORBIDITY AND MORTALITY IN HEMODIALYSIS PATIENTS
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批准号:2770492
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项目类别:
-
资助金额:$24.6万
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财政年份:1994
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负责人:STEVE J SCHWAB
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依托单位:
MORBIDITY AND MORTALITY IN HEMODIALYSIS PATIENTS
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批准号:6177118
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项目类别:
-
资助金额:$23.88万
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财政年份:1994
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负责人:STEVE J SCHWAB
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依托单位:
MORBIDITY AND MORTALITY IN HEMODIALYSIS PATIENTS
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批准号:2149909
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项目类别:
-
资助金额:$18.99万
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财政年份:1994
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负责人:STEVE J SCHWAB
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依托单位:
MODIFICATION OF DIET IN RENAL DISEASE STUDY
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批准号:3550879
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项目类别:
-
资助金额:$42.71万
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财政年份:1988
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负责人:STEVE J SCHWAB
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依托单位:
GENERAL CLINICAL RESEARCH CENTER
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批准号:7000453
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项目类别:
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资助金额:$147.94万
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财政年份:1976
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负责人:STEVE J SCHWAB
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依托单位:
EFFECT OF DIET ON PROGRESSIVE RENAL DISEASE
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批准号:3783377
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项目类别:
-
资助金额:$0.0万
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财政年份:--
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负责人:STEVE J SCHWAB
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依托单位:
海外基金