BEAT OSTEOPOROSIS: NOURISH & EXERCISE SKELETONS (BONE)

战胜骨质疏松症：滋养

• 批准号: 6388112
• 负责人: CHRISTINA D ECONOMOS
• 金额: $ 58.13万
• 依托单位: TUFTS UNIVERSITY MEDFORD
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-06-04 至 2004-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6388112
• 关键词: body composition; body physical activity; bone density; bone metabolism; calcium metabolism; child (0-11); clinical research; dietary calcium; disease /disorder prevention /control; health behavior; human subject; human therapy evaluation; longitudinal human study; muscle strength; nutrition related tag; osteoporosis; outcomes research; parent offspring interaction

Osteoporosis affects more than 28 million Americans and accounts for more than 1.5 million fractures annually, at a cost of 513.8 billion. One of the most effective ways to prevent osteoporosis is to build a strong, dense skeleton during the growing years to act as a reserve in later life. Furthermore, changes in individual behaviors and lifestyle preferences in younger children may last through the critical adolescent period and continue into adulthood, providing a lifetime of optimal bone health. The primary aim of this study is to develop, implement and evaluate a multi-faceted intervention in after-school programs that will increase bone accretion and muscular strength in early elementary school children. The intervention will include weight loading physical activity and calcium-rich snacks for children as well as age- appropriate, behaviorally focused active learning to promote skill building and self-competence. It will also include a parent/caregiver communications module that by provides specific activities and practical information to complement and reinforce the direct intervention with the children. A mascot and logo will be used to foster positive attitudes about calcium-rich foods and physical activity; incentives and goal setting will be used to encourage sustained behavior. One thousand eight hundred first and second grade children from 60 after-school programs in up to 10 diverse communities throughout Massachusetts will be randomized and studied for 24 months. Matched program groups will receive either The BONES Project (n=24), The BONES Project plus a parent/caregiver component (n=12); or they will serve as controls (n=24). Follow-up will continue for 12 months after the intervention period. The primary outcomes will be bone quality and muscular strength. Secondary outcomes will include physical activity levels, calcium consumption, body composition, self-perception of physical abilities and appearance, and influencing factors toward relevant healthy lifestyle behaviors, such as knowledge and attitudes. The control group will receive a "delayed" intervention after termination of the 36-month study. Focus group research with after-school program leaders, parents/caregivers, and children prior to initiation will provide information to optimize the campaign design. Findings from this study will promote our understanding of health behaviors in young children and the effect of parental involvement on these behaviors. Implementation of the same intervention within this widely diverse set of communities will guide appropriate cultural, community and socioeconomic-specific modifications and permit easier replication of the program. Because the intervention utilizes the existing after-school framework large numbers of children can be reached. Results from this study will provide an appropriate model for national replication and sustainability of a program to beat osteoporosis by nourishing and exercising skeletons early in life.

骨质疏松症影响超过2800万美国人，每年占150万次骨折，造成5138亿美元。预防骨质疏松症的最有效方法之一是在生长期间建立一个强大的骨骼骨骼，以在以后的生活中充当储备。此外，年幼儿童的个人行为和生活方式偏好的变化可能会持续到关键的青少年时期，并持续成年，从而提供了最佳的骨骼健康。这项研究的主要目的是在课后计划中开发，实施和评估多方面的干预措施，以增加早期小学儿童的骨积聚和肌肉力量。该干预措施将包括为儿童的体育锻炼和钙富含钙丰富的零食，以及适当的，以行为为主动的积极学习，以促进技能建立和自我能力。它还将包括父母/照顾者通信模块，该模块通过提供特定的活动和实用信息来补充和加强与孩子的直接干预。吉祥物和徽标将用于促进对富含钙的食物和体育锻炼的积极态度。激励措施和目标设定将用于鼓励持续的行为。来自马萨诸塞州多达10个不同社区的60个课后计划的一千八百名和二年级的孩子将被随机分配和研究24个月。匹配的程序组将接收骨骼项目（n = 24），骨骼项目以及父/照顾者组件（n = 12）;否则它们将用作控制（n = 24）。干预期后的随访将持续12个月。主要结果将是骨骼质量和肌肉力量。次要结果将包括体育锻炼水平，钙消耗，身体成分，对身体能力和外观的自我认知以及影响相关健康生活方式行为的因素，例如知识和态度。对照组终止36个月研究后，对照组将接受“延迟”的干预措施。在启动之前，与课后课程领导者，父母/照顾者和儿童进行焦点小组研究将提供信息以优化广告系列设计。这项研究的结果将促进我们对幼儿健康行为的理解以及父母参与对这些行为的影响。在这一广泛的社区中实施相同的干预措施将指导适当的文化，社区和社会经济特定的修改，并可以更轻松地复制该计划。因为干预利用现有的课后框架可以接触大量儿童。这项研究的结果将为一项计划的民族复制和可持续性提供适当的模型，以通过滋养和锻炼骨骼的早期来击败骨质疏松症。