课题基金 / 基金详情

HUMAN GROWTH HORMONE RELEASING FACTOR IN LONG TERM TREATMENT OF CHILD

HUMAN GROWTH HORMONE RELEASING FACTOR IN LONG TERM TREATMENT OF CHILD
儿童长期治疗中的人类生长激素释放因子
批准号：
6308580
负责人：
STEPHEN M ROSENTHAL
金额：
$1.75万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-12-01 至 2000-11-30
来源：
https://reporter.nih.gov/project-details/6308580
关键词：
child (0-11) child physical development clinical research endocrine disorder growth hormone releasing hormone hormone therapy human subject human therapy evaluation postnatal growth disorder somatotropin

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中文摘要
翻译
本研究的主要目的是评价在12-24个月期间每天一次皮下给予GRF 1-44在刺激患有下丘脑起源的生长激素分泌缺陷的儿童的生长速度方面的耐受性和功效。本研究由ICN Pharmaceuticals，Inc申办，是一项III期、每日单次给药、非随机、开放、门诊研究，每例患者作为其自身对照。6个月后将根据生长率评估疗效。
英文摘要
The primary objective of this study is to evaluate the tolerability and efficacy of the once-a-day subcutaneous administration of GRF 1-44 during 12-24 months in stimulating growth velocity in children with documented growth hormone secretion deficiency of hypothalamic origin. This study, sponsored by ICN Pharmaceuticals, Inc, is a Phase III, single daily administration, non-randomized, open, outpatient study, with each patient serving as his/her own control. Efficacy will be assessed after 6 months based on growth rate.
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