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VARIABILITY IN HEPATIC IRON CONCENTRATION FROM NEEDLE BIOPSY SPECIMEN

VARIABILITY IN HEPATIC IRON CONCENTRATION FROM NEEDLE BIOPSY SPECIMEN
针吸活检标本中肝铁浓度的变异性
批准号：
6308606
负责人：
PAUL R HARMATZ
金额：
$1.75万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-12-01 至 2000-11-30
来源：
https://reporter.nih.gov/project-details/6308606
关键词：
biopsy clinical research diagnosis quality /standard hemoglobinopathy human tissue iatrogenic disease iron poisoning liver metabolism

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中文摘要
翻译
接受长期输血治疗的镰状细胞性贫血或地中海贫血患者铁过载的风险很高。 我们想确定肝脏活检在测量铁过载方面的效果。 在本研究中，我们将在常规检测后使用该组织进行额外测量。 我们希望了解通过肝活检测量铁过载的准确性。
英文摘要
Patients with sickle cell anemia or thalassemia receiving chronic transfusion therapy are at a high risk of iron overload. We would like to determine how well liver biopsy is in measuring iron overload. In this study we will use this tissue after routine testing to take additional measurements. We hope to learn how accurately iron overload is being measured by liver biopsy.
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