ADAPTIVE RADIATION THERAPY

适应性放射治疗

• 批准号: 6376291
• 负责人: DI YAN
• 金额: $ 6.77万
• 依托单位: WILLIAM BEAUMONT HOSPITAL RESEARCH INST
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-01 至 2002-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6376291
• 关键词: clinical research; computed axial tomography; human mortality; human subject; human therapy evaluation; imaging /visualization /scanning; mathematical model; neoplasm /cancer radiation therapy; nonsmall cell lung cancer; outcomes research; prostate neoplasms; radiation therapy dosage

DESCRIPTION: (Adapted from the applicant's abstract): In this proposal, it is proposed to develop ART: a closed loop feedback process where the treatment is optimized on the basis of individual patient variation data obtained during the course of treatment. This goal will be accomplished through three specific aims: 1) Derive a model to predict the time-course of individual patent treatment variation, 2) Implement feedback of the information from the predictive model into a treatment planning system that will compensate for the variation, 3) Perform preliminary clinical studies of ART.

描述：（改编自申请人的摘要）：在本提案中， 提出了发展艺术：闭环反馈过程， 基于个体患者变化数据优化治疗 在治疗过程中获得。 这一目标将得以实现 通过三个具体目标：1）推导出一个模型来预测时间进程 2）实施个体患者治疗变化的反馈， 将来自预测模型的信息输入治疗计划系统， 将补偿变化，3）进行初步临床研究 条

项目成果

Estimating the dose variation in a volume of interest with explicit consideration of patient geometric variation.

在明确考虑患者几何变化的情况下估计感兴趣体积的剂量变化。

• DOI: 10.1118/1.1288683
• 发表时间: 2000
• 期刊: Medical physics
• 影响因子: 3.8
• 作者: Lockman,DM;Yan,D;Wong,J
• 通讯作者: Wong,J

The influence of small bowel motion on both a conventional three-field and intensity modulated radiation therapy (IMRT) for rectal cancer.

• DOI: 10.1016/j.canrad.2004.08.001
• 发表时间: 2004-10-01
• 期刊: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
• 作者: Nuyttens, Joost J;Robertson, John M;Martinez, Alvaro
• 通讯作者: Martinez, Alvaro