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A DNA VACCINE TO PREVENT TRANSMISSION OF HUMAN MALARIA

A DNA VACCINE TO PREVENT TRANSMISSION OF HUMAN MALARIA
预防人类疟疾传播的 DNA 疫苗
批准号:
6362447
负责人:
Nirbhay Kumar
金额:
$30.73万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2000
资助国家:
美国
项目状态:
已结题
起止时间:
2000-03-01 至 2004-02-29

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中文摘要
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英文摘要
DESCRIPTION (Adapted from the Applicant's Abstract): The goal of this application is to develop a transmission blocking vaccine to Plasmodium falciparum. This vaccine is meant to induce antibodies which bind to antigens present on the surface of male and female gameites and parasites developing in the mosquito midgut. The main candidate antigen is Pfs25, a surface protein that is expressed at the onset of gametogenesis. The vaccine will be based on DNA vaccines given either alone or in a prime-boast regimen with protein vaccines.
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Combination Vaccines to Interrupt Malaria Transmission
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  • 项目类别:
  • 资助金额:
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  • 财政年份:
    2017
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Combination Vaccines to Interrupt Malaria Transmission
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Identification of Transmission blocking epitopes on P. vivax 48/45 protein
  • 批准号:
    8986156
  • 项目类别:
  • 资助金额:
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  • 财政年份:
    2014
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Rational Approach to Optimize Immune Potency of DNA Vaccines
  • 批准号:
    8676649
  • 项目类别:
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    $18.81万
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    2013
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