Malaria Training and Research Capacity Building in Southern Africa

描述（由申请人提供）：南部非洲疟疾培训和研究能力建设的长期目标是在南部非洲建立一个卓越的疟疾研究中心。拟议的项目建立在我们以前在津巴布韦的疟疾研究和培训项目取得成功的基础上。我们建议继续加强我们目前的学员（两名博士），同时将疟疾研究和培训扩展到赞比亚和邻近的南部非洲国家。除了与以前的学员保持密切的研究联系外，我们还建议创建特定的培训，以满足当地研究界的迫切需求。这将以约翰·霍普金斯大学教员提供的最先进的研究方法和技术的短期培训的形式进行。此外，将在赞比亚提供四种不同的培训课程：(1)疟原虫生物学和治疗；(2)疟疾控制：监测和评价；(3)基础免疫学和微生物免疫学；(4)昆虫学。这些课程将由约翰霍普金斯大学的教员和来自赞比亚各中心的科学家合作提供，特别是来自赞比亚大学医学院教学医院、马查疟疾研究所和恩多拉热带病研究中心的科学家。这些课程也将包括我们以前在津巴布韦接受培训的同事。在赞比亚开展的各种疟疾研究和培训活动将提供一种结构，以便将从培训课程和分子生物学、微生物学、免疫学、生态学、分子流行病学、基因组学和人口遗传学方面的有针对性的专门研究培训中获得的知识应用于当地问题，从而在该区域建立一个由十几名科学家组成的综合研究界。

DESCRIPTION (provided by applicant): The long-term objective of the Malaria Training and Research Capacity Building in Southern Africa is to create a center of excellence for malaria research in Southern Africa. The proposed program builds upon our previous success with the Malaria Research and Training Program in Zimbabwe. We propose to continue to strengthen our current trainees (two PhD) while extending malaria research and training to Zambia and neighboring Southern African countries. In addition to maintaining strong research ties with our former trainees, we propose to create specific training to satisfy immediate needs of the local research community. This would occur in the form of short-term training in state-of-the-art research methods and techniques offered by Johns Hopkins faculty. In addition, four different training courses will be offered in Zambia: (1) Plasmodium Biology and Treatment, (2) Malaria Control: Monitoring and Evaluation, (3) Basic Immunology and Microbial Immunity and (4) Entomology. The courses will be offered in partnership between Johns Hopkins University faculty and scientists from various centers in Zambia, especially the School of Medicine University Teaching Hospital, University of Zambia, Malaria Institute at Macha and Tropical Disease Research Center at Ndola. These courses will also involve our former training grant colleagues from Zimbabwe. The various malaria research and training activities conducted in Zambia will provide a structure for the application of knowledge gained from training courses and specialized targeted research training in molecular biology, microbiology, immunology, ecology, molecular epidemiology, genomics and population genetics to local issues resulting in the creation of a comprehensive research community of more than a dozen scientists in the region.