CORE--CANCER CONTROL RESEARCH PROGRAM

核心——癌症控制研究计划

• 批准号: 6430480
• 负责人: JEFFREY P KRISCHER
• 金额: $ 30.53万
• 依托单位: UNIVERSITY OF SOUTH FLORIDA
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-02-19 至 2006-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6430480
• 关键词: behavioral /social science research tag; biomarker; biomedical facility; cancer prevention; cancer risk; caregivers; diagnosis design /evaluation; early diagnosis; genetic susceptibility; neoplasm /cancer diagnosis; neoplasm /cancer genetics; psychological aspect of cancer; quality of life

Description: (Applicant's Description) The Cancer Control Research Program remains focused on the reduction of the burden of cancer on individuals and society. The specific aims are the application of multidisciplinary research to: (1) Identify markers that predict increased cancer susceptibility, (2) Evaluate promising interventions for the prevention of cancer, (3) Develop and test new early detection strategies and (4) Evaluate interventions to improve the quality of life for cancer patients and their care-givers. Research in cancer susceptibility/carcinogenesis has received expanded funding along with the recruitment of high-risk cohorts that are followed longitudinally. Prevention studies are underway in breast, lung and prostate cancer. Imaging research has progressed and focused on translational efforts providing evaluation of important CAD methods in clinical practice. Behavioral research funded studies address the entire spectrum of cancer control research from assessing the determinants of risk perception to quality of life and health outcomes. The infrastructure has expanded to include the DOD-funded Advanced Cancer Detection Center and the Center for Mathematical Modeling of Image Data Across the Sciences. Both new centers provide a focus for Cancer Control research and support pilot studies that have led to peer-reviewed funding. In addition, Lifetime Cancer Screening has grown to serve more than 17,000 patient encounters annually and houses multiple cancer control research projects. Program growth has been remarkable with an increase in annual funding from $3.8 to $8.8 million in only two years. Collaborations with basic science and clinical investigations have expanded rapidly through targeted recruitment, investment of institutional resources and recently awarded collaborative grants. This has resulted in laboratory scientists, clinical investigators, nurses and health services researchers jointly addressing the spectrum of research from basic science to pre-clinical to clinical translation.

描述：（申请人描述）癌症控制研究计划 仍然专注于减少癌症对个人的负担， 社会具体目标是多学科研究的应用 目的：（1）确定预测癌症易感性增加的标志物，（2） 评估有希望的预防癌症的干预措施，（3）制定和 测试新的早期检测策略和（4）评估干预措施，以改善 癌症患者及其护理人员的生活质量。研究 癌症易感性/致癌性已经得到了沿着扩大的资助， 招募高风险队列，并对其进行纵向跟踪。 乳腺癌、肺癌和前列腺癌的预防研究正在进行中。成像 研究取得了进展，并重点关注转化工作， 评价临床实践中重要的CAD方法。行为研究 资助的研究涉及癌症控制研究的整个范围， 评估风险感知对生活质量和健康的决定因素 结果。基础设施已经扩展到包括国防部资助的高级 癌症检测中心和图像数据数学建模中心 在科学界。这两个新中心都为癌症控制提供了一个重点 研究和支持试点研究，导致同行审查的资金。在 此外，终身癌症筛查已发展到为17，000多人提供服务， 患者每年都会遇到，并拥有多项癌症控制研究 项目项目增长显著， 仅在两年内就从380万美元增加到880万美元。合作与 基础科学和临床研究迅速扩大， 有针对性的招聘，机构资源的投资，以及最近 授予合作赠款。这导致实验室科学家， 临床研究人员、护士和卫生服务研究人员联合 从基础科学到临床前， 临床翻译