Clinical Research to Improve Drug Abuse Treatment Entry

改善药物滥用治疗进入的临床研究

• 批准号: 6522924
• 负责人: THOMAS P O'TOOLE
• 金额: $ 13.15万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-30 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6522924
• 关键词: HIV infections; behavioral /social science research tag; clinical trials; drug abuse; drug abuse therapy; health care service evaluation; health services research tag; high risk behavior /lifestyle; hospital utilization; human subject; human therapy evaluation; longitudinal human study; motivation; outcomes research; outpatient care; patient care planning; patient oriented research; posthospitalization care; relapse /recurrence; substance abuse epidemiology; therapy compliance

DESCRIPTION: (provided by applicant) This is a request for a Mentored Patient-Oriented Career Development Award. Over the five years of the award, the candidate will conduct one observational study and two clinical trials of hospital-based interventions to improve drug abuse treatment entry and retention among medicine inpatients. Primary mentorship will be provided by Drs. George Bigelow and Daniel Ford. Additional mentoring and tutorial assistance will be provide by Drs. Maxine Stitzer, Laura Morlock, and Carlo DiClemente. The goals for this career development project are to better understand the role of the medical hospitalization on motivation for treatment and readiness for change and to assess whether clinical interventions can improve subsequent treatment entry and retention. Specific aims are to (1) identify factors within an acute hospitalization episode that influence a person's motivation for and actual entry into treatment. (2) Determine whether hospital-based clinical interventions improve treatment entry and retention upon hospital discharge. (3) Determine whether these interventions effect subsequent health utilization and management of concurrent HIV infection. Three sub-studies will be conducted on a cohort of substance abusing patients admitted to the medicine service at Johns Hopkins Hospital: (a) an observational, longitudinal study of substance abusing medicine inpatients; (2) a randomized clinical trials of peer mentor-structured transitional support and (3) a quasi-experimental study of concurrently administered substance abuse treatment. This program of research and training will provide important information on the acute medical hospitalization for substance abusing patients and how it can best be structured to improve health care and substance abuse outcomes.

描述：（申请人提供） 这是一份申请，要求获得以病人为导向的职业发展奖。 在获奖的五年里，候选人将进行一次观察 一项研究和两项基于医院的干预措施的临床试验， 住院病人滥用药物治疗的进入和滞留。初级 导师将由乔治毕格罗博士和丹尼尔福特博士提供。额外 指导和辅导援助将提供博士。玛克辛Stitzer，劳拉 Morlock和Carlo DiClemente。本职业发展项目的目标 是为了更好地理解医疗住院对动机的作用， 治疗和准备改变，并评估是否临床 干预措施可以改善随后的治疗进入和保留。 具体目标是（1）确定急性住院的因素 影响一个人的动机和实际进入的情节 治疗(2)确定基于医院的临床干预措施是否得到改善 出院时的治疗进入和保留。(3)确定是否 这些干预措施影响随后的健康利用和管理， 同时感染艾滋病毒。将对一个队列进行三个子研究， 在约翰霍普金斯医院接受药物治疗的滥用药物的病人 医院：（a）对药物滥用的观察性纵向研究 内科住院患者;（2）同行导师结构的随机临床试验 过渡性支持和（3）同时进行的准实验研究 进行药物滥用治疗这项研究和培训计划 将提供有关急性医疗住院的重要信息， 药物滥用患者以及如何最好地改善健康 护理和药物滥用的结果。