Clinical Research to Improve Drug Abuse Treatment Entry

改善药物滥用治疗进入的临床研究

• 批准号: 6800549
• 负责人: THOMAS P O'TOOLE
• 金额: $ 13.15万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-30 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6800549
• 关键词: HIV infections; behavioral /social science research tag; clinical trials; drug abuse; drug abuse therapy; health care service evaluation; health services research tag; high risk behavior /lifestyle; hospital utilization; human subject; human therapy evaluation; longitudinal human study; motivation; outcomes research; outpatient care; patient care planning; patient oriented research; posthospitalization care; relapse /recurrence; substance abuse epidemiology; therapy compliance

DESCRIPTION: (provided by applicant) This is a request for a Mentored Patient-Oriented Career Development Award. Over the five years of the award, the candidate will conduct one observational study and two clinical trials of hospital-based interventions to improve drug abuse treatment entry and retention among medicine inpatients. Primary mentorship will be provided by Drs. George Bigelow and Daniel Ford. Additional mentoring and tutorial assistance will be provide by Drs. Maxine Stitzer, Laura Morlock, and Carlo DiClemente. The goals for this career development project are to better understand the role of the medical hospitalization on motivation for treatment and readiness for change and to assess whether clinical interventions can improve subsequent treatment entry and retention. Specific aims are to (1) identify factors within an acute hospitalization episode that influence a person's motivation for and actual entry into treatment. (2) Determine whether hospital-based clinical interventions improve treatment entry and retention upon hospital discharge. (3) Determine whether these interventions effect subsequent health utilization and management of concurrent HIV infection. Three sub-studies will be conducted on a cohort of substance abusing patients admitted to the medicine service at Johns Hopkins Hospital: (a) an observational, longitudinal study of substance abusing medicine inpatients; (2) a randomized clinical trials of peer mentor-structured transitional support and (3) a quasi-experimental study of concurrently administered substance abuse treatment. This program of research and training will provide important information on the acute medical hospitalization for substance abusing patients and how it can best be structured to improve health care and substance abuse outcomes.

描述：（由申请人提供） 这是申请以患者为导向的职业发展奖。 在获奖的五年内，候选人将进行一项观察 以医院为基础的干预措施改善药物的研究和两项临床试验 药物住院患者的滥用治疗进入和保留情况。基本的 博士将提供指导。乔治·毕格罗和丹尼尔·福特。额外的 博士将提供指导和辅导帮助。劳拉·玛克辛·斯蒂策 莫洛克和卡洛·迪克莱门特。该职业发展项目的目标 是为了更好地理解住院治疗对动机的作用 治疗和改变的准备，并评估临床是否 干预措施可以改善后续治疗的进入和保留。 具体目标是 (1) 确定急性住院治疗中的因素 影响一个人的动机和实际进入的事件 治疗。 (2) 确定以医院为基础的临床干预措施是否有所改善 出院后的治疗进入和保留。 (3)判断是否 这些干预措施会影响随后的健康利用和管理 同时感染艾滋病毒。将对一组人群进行三项子研究 约翰·霍普金斯大学医疗服务中心收治药物滥用患者 医院：(a) 对药物滥用的观察性纵向研究 医学住院病人； (2) 同行导师结构的随机临床试验 过渡性支持和（3）同时进行的准实验研究 进行药物滥用治疗。该研究和培训计划 将提供有关急性内科住院的重要信息 药物滥用患者以及如何最好地构建它来改善健康 护理和药物滥用结果。