Neonatal Chest Phantom for Computed Radiography Testing

用于计算机放射检查测试的新生儿胸部体模

• 批准号: 6337640
• 负责人: Steven Don
• 金额: $ 10万
• 依托单位: GAMMEX, INC.
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-20 至 2003-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6337640
• 关键词: bioimaging /biomedical imaging; computer assisted diagnosis; diagnosis quality /standard; digital imaging; human data; image processing; laboratory rabbit; model design /development; newborn human (0-6 weeks); phantom model; thoracic radiography

This proposal's long-term goal is to develop radiographic phantoms to address the following critical needs in the emerging field of digital x- ray imaging: quality control procedures for daily operations; quality assurance methods for users to evaluate products, perform acceptance testing and determine optimum system operating parameters; development tools for manufacturers to test new hardware and software products. Because neonatal chest radiography is technically challenging and has profound radiation dose implications, it was selected as the focal point for phantom development. The phantom will contain test objects for objective and subjective measurement of system performance. Phase 1 of this project includes these Specific Aims: 1) Establish parameters that define the neonatal chest phantom; 2) Construct prototype phantoms based on the above parameters; 3) Evaluate the suitability of prototype phantoms for clinical tasks. Successful phantom design will be determined by the appearance and histogram analysis of images; the attenuation values of anatomic structures; and the diagnostic performances of radiologists with detection of test objects within the phantom. The clinical significance of this phantom is that it could be used to assure optimal performance of equipment and minimize x-ray exposure and the concomitant risk of induced malignancy to neonates. PROPOSED COMMERCIAL APPLICATIONS: A new class of x-ray phantoms will be developed for use with computed radiography and other digital x-ray imaging devices. The phantom will be used in quality assurance programs, as a design tool for equipment vendors, and as a research tool for reducing radiation exposure while maintain image quality. This Phase 1 feasibility proposal will initially develop a neonatal chest phantom as it tests the limits of computed radiography. The worldwide market for this phantom is estimated to be $27,000,000 to $37,000,000 over the next five to seven years for the pediatric phantom alone. With the extension to a new class of digital x-ray imaging phantoms, the potential market should exceed $150,000,000.

该提案的长期目标是开发射线照相幻影，以满足数字X射线成像新兴领域的以下关键需求：日常操作的质量控制程序;用户评估产品、进行验收测试和确定最佳系统操作参数的质量保证方法;制造商测试新硬件和软件产品的开发工具。由于新生儿胸部X线摄影在技术上具有挑战性，并且具有深刻的辐射剂量影响，因此将其选为体模开发的重点。体模将包含用于系统性能的客观和主观测量的测试对象。本项目的第1阶段包括以下具体目标：1）建立定义新生儿胸部体模的参数; 2）根据上述参数构建原型体模; 3）评价原型体模对临床任务的适用性。成功的体模设计将通过图像的外观和直方图分析、解剖结构的衰减值以及放射科医生检测体模内测试对象的诊断性能来确定。该体模的临床意义在于，它可用于确保设备的最佳性能，并最大限度地减少X射线照射和新生儿诱发恶性肿瘤的伴随风险。拟议的商业应用：将开发一种新的X射线体模，用于计算机X射线摄影和其他数字X射线成像设备。该体模将用于质量保证计划，作为设备供应商的设计工具，并作为减少辐射暴露同时保持图像质量的研究工具。本第1阶段可行性提案将首先开发新生儿胸部体模，以测试计算机X射线摄影的局限性。在未来5 - 7年内，仅儿科体模的全球市场估计为27，000，000 - 37，000，000美元。随着扩展到一个新的数字X射线成像幻影类，潜在的市场应该超过1.5亿美元。

项目成果

Neonatal chest computed radiography: image processing and optimal image display.

新生儿胸部计算机射线照相：图像处理和最佳图像显示。

• DOI: 10.2214/ajr.05.0733
• 发表时间: 2007
• 期刊: AJR. American journal of roentgenology
• 作者: Don,Steven;Whiting,BruceR;Ellinwood,JacquelynS;Foos,DavidH;Kronemer,KeithA;Kraus,RichardA
• 通讯作者: Kraus,RichardA