INTERACTIVE 4D VISUALIZATION OF CONGENITAL HEART DISEASE

先天性心脏病的交互式 4D 可视化

• 批准号: 6391271
• 负责人: MARIJN EDUARD BRUMMER
• 金额: $ 9.96万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-05-01 至 2003-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6391271
• 关键词: bioimaging /biomedical imaging; cardiovascular imaging /visualization; child (0-11); clinical research; computer assisted diagnosis; computer program /software; computer system design /evaluation; congenital cardiovascular disorder; congenital heart disorder; diagnosis design /evaluation; functional magnetic resonance imaging; heart imaging /visualization /scanning; human subject; image enhancement; infant human (0-1 year); interactive multimedia

DESCRIPTION (Taken from application abstract): Development and clinical testing of a new family of software display techniques for cardiovascular magnetic resonance imaging (MRI) data are proposed. These efforts are anticipated to enhance the diagnostic process and facilitate currently challenging decisions on therapy and patient management of children with severe congenital heart disease. In particular, assessment of hypoplastic left and right heart syndromes and univentricular heart require improved visualization and function quantification tools for evaluation and monitoring of severity and functional status. The initial design of the system is largely completed. Design features of the software system are footed on recent improvements in widely available 3-D rendering hardware and on observations made during 11 years of clinical experience with cardiac MRI at the investigation site During the first year of the project a clinically usable prototype can be delivered for testing and user feedback, including a highly streamlined image data pipeline, sophisticated contemporary user interface, and other features essential for extensive clinical evaluation. The proposed dynamic 3-D display technique combines a maximum of anatomical information available in a multi-slice ECG-triggered cine-MRI scan of the heart, by displaying all slice images simultaneously in correct 3-D geometric perspective in dynamic fashion (a cyclic movie of the beating heart). A user can manipulate in real-time the displayed slice objects to improve visualization of regional anatomy, generate reformatted views along cutting planes on-the-fly, and annotate the display for other observers by highlighting 3-D regions of interest. The proposed effort includes (1) development of first prototype using extensive preexisting in-house developed software libraries, (2) clinical evaluation of the technique from the second year of the project onwards, (3) implementation of enhancements including quantitation and display of essential cardiac function parameters including hemodynamic data and follow-up on user feedback, and adding limited DICOM I/O functionality.

描述（取自应用摘要）：开发和临床 对心血管的新软件显示技术的测试 提出了磁共振成像（MRI）数据。 这些努力是 预计可以增强诊断过程并促进 关于儿童的治疗和患者管理的挑战性决定 严重的先天性心脏病。 特别是，评估不形成型 左右心脏综合征和单心脏心脏需要改善 可视化和功能量化工具用于评估和 监视严重性和功能状态。 系统的初始设计在很大程度上完成了。 设计功能 该软件系统基于最新可用的改进 3-D渲染硬件和在临床11年期间进行的观察结果 第一年在调查网站上具有心脏MRI的经验 在该项目中，临床上可用的原型可以进行测试 和用户反馈，包括高度精简的图像数据管道， 复杂的现代用户界面，以及其他对 广泛的临床评估。 提出的动态3-D显示技术结合了最大解剖学 在多块ECG触发的Cine-MRI扫描中可用的信息 心脏，通过在正确的3-D中同时显示所有切片图像 以动态方式的几何视角（击败的循环电影 心）。 用户可以实时操纵显示的切片对象 改善区域解剖结构的可视化，并产生重新格式化的观点 fly切平面，并通过 强调3D兴趣区域。 拟议的工作包括（1）使用使用 广泛的内部开发软件库，（2）临床 从项目的第二年开始评估技术，（3） 实施增强功能，包括定量和显示 必需的心脏功能参数，包括血液动力学数据和 跟进用户反馈，并添加有限的DICOM I/O功能。