突触前蛋白神经损伤的表征-猫眼课题宝

突触前蛋白神经损伤的表征

批准号：

6405037

负责人：

Benjamin Arthur Eaton

金额：

$4.02万

依托单位：

UNIVERSITY OF CALIFORNIA, SAN FRANCISCO

依托单位国家：

美国

项目类别：

财政年份：

2001

资助国家：

美国

项目状态：

未结题

起止时间：

2001-08-01 至

来源：

https://reporter.nih.gov/project-details/6405037

关键词：

Drosophilidae developmental genetics developmental neurobiology electrophysiology gene induction /repression gene mutation genetically modified animals glutamate receptor nerve /myelin protein neurogenetics neuromuscular junction protein structure function receptor expression synaptogenesis

项目摘要

项目成果

Benjamin Arthur Eaton的其他基金

相似基金

相关文献

中文摘要

翻译

点击翻译按钮获取中文摘要

英文摘要

DESCRIPTION (provided by applicant): In this proposal I plan to investigate the formation and function of the synaptic bouton at the Drosophila NMJ. The control of the differentiation of the synapse presynaptically is poorly understood. One manifestation of this differentiation is the formation of the synaptic bouton. Synaptic boutons are found at nearly all synapses but the formation of these varicosities as well as their function has not been addressed experimentally. Preliminary data from the novel Drosophila gene nerve-wracked suggests that this gene specifically controls the formation of boutons at the NMJ. I plan to further characterize this gene and use this reagent to investigate the formation and function of synaptic boutons.

期刊论文(0)

专著(0)

科研奖励(0)

会议论文