Photoinitiation rate effects on multimethacrylate resin

光引发率对多甲基丙烯酸酯树脂的影响

• 批准号: 6323732
• 负责人: SHELDON M NEWMAN
• 金额: $ 11.63万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-05-01 至 2003-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6323732
• 关键词: biomaterial evaluation; chemical kinetics; composite resins; light intensity; photoactivation; physical property; polymerization; polymethacrylate; predoctoral investigator; tooth filling

Dental composite restorative materials are based on photoinitiated methacrylate comonomer systems. The rate of initiation is currently being altered by the use of light sources of different intensities. There are theories as to the potential effects of varying the initiation rates. A fundamental understanding of the impact of initiation rates on the conversion and networking of various resin systems will help in the development of better restorative materials. The principle goal of this investigation is to identify the effects on conversion and the resulting properties as a result of varying the rate of initiation. Initially, the total energy fluxed will be matched for the various light intensities (integrated to the photoinitiator absorbtion spectra) by altering the exposure times. A dimethacrylate comonomer resin will be investigated initially using a visible light photosensitizer. The conversion can be monitored using near IR. The following properties will be investigated in the resulting polymer: flexural strength, flexural modulus, Tg, and polymerization shrinkage. The comonomer system primarily tested will be BisGMA/TEGDMA as the baseline for varying light intensity. Other comonomers using ethoxybisGMA and urethane dimethacrylate will also be evaluated to ascertain the effects of varying viscosity and monomer flexibility. The career development planned with this work includes the completion of graduate course work that will enable the completion of a PhD in materials sciences at the Colorado School of Mines. The experience will provide the background to move from a primarily teaching position to a contributing researcher in fundamental polymer development. The University of Colorado Health Sciences Center is developing a new biomaterials research center and establishing relations with the Colorado School of Mines Metallurgical and Materials Engineering Department in its new specialty area of biomaterials. Intercampus research is also growing with the polymer chemistry group in the Chemical Engineering Department at the University of Colorado, Boulder.

牙科复合修复材料是基于光引发 甲基丙烯酸酯共聚单体体系。目前，启动率 通过使用不同强度的光源来改变。有 关于改变起爆率的潜在影响的理论。一 基本了解引发速率对转化率的影响 各种树脂系统的网络化将有助于开发更好的 修复材料。本次调查的主要目的是确定 对转化的影响和作为变化的结果的性质 启动率。最初，总的能量通量将与 各种光强度（与光引发剂吸收率积分 光谱）。二甲基丙烯酸酯共聚单体树脂将 首先使用可见光光敏剂进行研究。转换 可以使用近红外进行监测。将研究以下特性 在所得聚合物中：弯曲强度、弯曲模量、Tg和 聚合收缩主要测试的共聚单体体系将是 BisGMA/TEGDMA作为改变光强度的基线。其它共聚单体 使用乙氧基双GMA和氨基甲酸酯二甲基丙烯酸酯也将进行评估， 确定不同粘度和单体柔性的影响。 这项工作规划的职业发展包括完成 研究生课程的工作，这将使在材料博士学位的完成 在科罗拉多矿业学院学习自然科学。经验将提供 从一个主要的教学位置移动到一个贡献的背景 基础聚合物开发研究员。 科罗拉多大学健康科学中心正在开发一种新的 生物材料研究中心，并与科罗拉多建立关系 矿业学院冶金与材料工程系新建 生物材料专业领域。校园间的研究也随着 化学工程系高分子化学组， 科罗拉多大学博尔德分校。