AN ELECTRICAL IMPEDANCE TOMOGRAPHY HYPERTHERMIA MONITOR

电阻抗断层扫描热疗监测仪

• 批准号: 6337764
• 负责人: WILLIAM D TIMMONS
• 金额: $ 13.05万
• 依托单位: ELECTROSONICS MEDICAL INC.
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-17 至 2002-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6337764
• 关键词: bioengineering /biomedical engineering; bioimaging /biomedical imaging; biomedical equipment development; biosensor device; clinical biomedical equipment; computer program /software; computer system design /evaluation; electrical conductance; electrical impedance; electrodes; electronic recording system; miniature biomedical equipment; neoplasm /cancer thermotherapy; noninvasive diagnosis; patient monitoring device; phantom model; thermography; thermometry; tomography; voltage /patch clamp

DESCRIPTION (Provided by Applicant): Hyperthermic cancer treatment is an increasingly important adjuvant to chemotherapy and other radiation procedures. Recent advances in multi-element, focused and scanning hyperthermia devices have increased the accuracy of 2D and 3D power deposition, requiring more advanced thermometry systems for adequate feedback control and treatment monitoring. Current invasive thermometry devices do not provide accurate thermal distribution images, while non-invasive methods such as CT and MRI are expensive and do not provide continuous imaging. The proposed device involves Electrical Impedance Tomography (EIT) to generate impedance maps of the tissue, which can then be converted to a temperature image. EIT will provide the following features: accurate thermal distribution maps, continuous monitoring, mobility, inexpensive, noninvasive. Research in EIT has established its effectiveness in both in-vitro and in-vivo thermometry. To this point, however, development has focused on reconstruction, not hardware. BIOMEC will create a device that will incorporate electronic miniaturization and the adaptability to accommodate new electrode switching schemes and improved reconstruction algorithms. This repackaged and compact design will take BIT from the research lab to the commercial marketplace. This project involves the development of a platform device, which can be tailored to thermometry and other EIT applications, in Phase II. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE

描述（由申请人提供）：高温癌症治疗是一种治疗癌症的方法。 越来越重要的辅助化疗和其他放射程序。 多元件聚焦扫描热疗装置的最新进展 提高了2D和3D功率沉积的精度，需要更多的 先进的温度测量系统，用于充分的反馈控制和治疗 监测.当前的侵入式测温装置不能提供准确的温度测量。 热分布图像，而非侵入性方法，如CT和MRI， 昂贵且不提供连续成像。申报器械涉及 电阻抗断层扫描（EIT），以生成组织的阻抗图， 然后可以将其转换为温度图像。EIT将提供 具有精确的热分布图，连续监测， 移动性，廉价，非侵入性。EIT的研究已经建立了其 在体外和体内温度测量中的有效性。然而，到目前为止， 发展的重点是重建，而不是硬件。BIOMEC将创建一个 一种将电子小型化和适应性结合在一起的装置， 适应新的电极切换方案和改进的重建 算法这种重新包装和紧凑的设计将采取位从研究 实验室到商业市场。该项目涉及开发一个 平台设备，可定制用于温度测量和其他EIT 应用程序，在第二阶段。 拟议商业应用：不可用