Cold High-Level Disinfectant for Medical Instruments

医疗器械冷高效消毒剂

• 批准号: 6401469
• 负责人: Rajiv Kumar Satsangi
• 金额: $ 9.9万
• 依托单位: RANN RESEARCH CORPORATION
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-01 至 2003-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6401469
• 关键词: antiseptic sterilization; cold temperature; disinfectants; technology /technique development

DESCRIPTION (provided by applicant): We propose to develop a novel cold high-level disinfecting/sterilization solution product for the treatment of heat sensitive medical equipments, especially expensive flexible fiberoptic endoscopes. The product will eliminate exposure of personnel to glutaraldehyde vapors; it will be rapidly tuberculocidal at lower temperature, non-corrosive, and cost effective. Our research will include the synthesis, purification and characterization of a family of active compounds. We will formulate these compounds into product for study their tuberculocidal activity using the AOAC Quantitative TB Test as a measuring standard for their high-level disinfection properties. This research proposes to combine the known benefits of the glutaraldehyde molecule with activity enhancing features of synergistic compounds into one molecule to produce a product that is capable of high level disinfection in 10-15 minutes at lower temperature, is reusable, and non-corrosive especially with heat sensitive medical endoscopic equipments. The long term objective of this research is to commercialize this product, which because of its activity at low concentration and temperature, will produce: (1 about less exposure to healthcare professionals;(2) faster equipment turn-around times and be non-corrosive to sensitive medical equipments, which will result in lower healthcare costs. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE

描述（由申请人提供）：我们建议开发一种新的感冒药， 高水平消毒/灭菌溶液产品，用于治疗 热敏医疗设备，特别是昂贵的柔性光纤 内窥镜该产品将消除人员暴露于戊二醛 蒸汽;在较低温度下可迅速杀灭结核菌，无腐蚀性， 和成本效益。我们的研究将包括合成，纯化和 表征活性化合物家族。我们将制定这些 使用AOAC将化合物转化为产品以研究其抗结核活性 结核病定量检测作为其高水平消毒的衡量标准 特性.本研究建议将联合收割机的已知益处 具有协同增效活性增强特征的戊二醛分子 将化合物合成一个分子，以产生能够高水平 在较低温度下10-15分钟内消毒，可重复使用， 无腐蚀性，特别适用于热敏医疗内窥镜设备。的 这项研究的长期目标是使这种产品商业化， 由于其在低浓度和温度下的活性，将产生：（1 关于减少接触医疗保健专业人员;（2）更快的设备 周转时间短，对敏感的医疗设备无腐蚀性， 将导致更低的医疗成本。 拟议商业应用：不可用