LARYNGEAL ENDOSCOPE WITH CALIBRATED SIZING FUNCTION

具有校准尺寸功能的喉内窥镜

• 批准号: 6292929
• 负责人: DAVID I. ROSEN
• 金额: $ 9.97万
• 依托单位: PHYSICAL SCIENCES, INC
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-06-01 至 2002-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6292929
• 关键词: bioengineering /biomedical engineering; bioimaging /biomedical imaging; biomedical equipment development; fiber optics; laryngoscopy; lasers; measurement; miniature biomedical equipment; video recording system

DESCRIPTION (Verbatim from the Applicant's Abstract): Laryngeal videoendoscopy combined with stroboscopy is now a mainstay for clinically assessing how the larynx functions to produce voice. Evaluation of the video imagery is currently limited to subjective visual judgments that can result in diminished reliability. A method enabling dimensional calibration of the images, and thus quantification of important vocal parameters, would greatly enhance the clinical and research capabilities of videoendoscopy with stroboscopy. Thus, the main goal of the proposed project is to investigate the feasibility of developing a laser-based projection system for dimensional calibration of laryngeal videoendoscopic images. The longer-term objective is to develop technology that is widely applicable to flexible endoscopy of the upper airway (including larynx). The near-term focus will be to develop an optical-based object sizing system for a flexible fiberoptic transnasal nasopharyngoscope. The Phase I tasks to be performed include: (1) developing a miniaturized design for a reference beam delivery channel compatible with the small caliber and flexibility required of a nasopharyngoscope, (2) specifying requirements for a reference beam laser illumination source compatible with videostroboscopic operation, (3) quantifying the object measurement accuracy achievable with such a system, and (4) developing a preliminary engineering design for a complete system suitable for clinical investigations. The Phase II effort would entail: (1) construction of a complete clinical prototype of the calibrated endoscope system, and (2) extensive clinical testing of the system at the Massachusetts Eye and Ear Infirmary (MEEI). PROPOSED COMMERCIAL APPLICATION: The market potential for a user-friendly calibration system customized for laryngeal video-stroboscopy is estimated to be several hundred units in the U.S. Similar systems for more general use flexible endoscopy of the upper airway (including larynx) have a potential worldwide market of up to several thousand units. The latter market reflects the large number of ototolaryngologists that use such scopes in routine clinical practice.

描述（来自申请人摘要的逐字描述）：喉视频内窥镜检查 与频闪镜相结合，现在是临床评估 喉的功能是发出声音。目前正在评估视频图像， 仅限于主观的视觉判断， 可靠性一种能够对图像进行尺寸校准的方法， 重要的声音参数的量化，将大大提高 视频内窥镜与频闪镜的临床和研究能力。因此，在本发明中， 该项目的主要目标是研究 开发一种基于激光的投影系统， 喉内窥镜图像。长期目标是发展 广泛适用于上气道柔性内窥镜检查的技术 （包括喉）。 近期的重点将是开发一种基于光学的物体尺寸测量系统 用于柔性光纤经鼻鼻咽镜。第一阶段的任务是 所进行的包括：（1）开发用于参考光束的小型化设计 输送通道兼容小口径和灵活性要求， 鼻咽镜，（2）规定参考光束激光器的要求 与视频频闪镜操作兼容的照明源，（3） 量化利用这种系统可实现的对象测量精度，以及 (4)为一个完整的系统开发初步的工程设计， 用于临床研究。第二阶段的工作将包括：（1）建造 校准内窥镜系统的完整临床原型，以及（2） 在马萨诸塞州眼耳医院对该系统进行了广泛的临床测试 医务室（MEEI）。 拟定商业应用： 用户友好的喉校准系统的市场潜力 视频频闪检查在美国估计有几百台。 更普遍使用的上呼吸道（包括喉）柔性内窥镜具有潜力 全球市场规模达数千台。 后一个市场反映了大 在常规临床实践中使用这种内窥镜的耳鼻喉科医生的数量。