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MAGNETIC RESONANCE PARAMETERS AS PREDICTORS OF NEUROLOGICAL OUTCOME

MAGNETIC RESONANCE PARAMETERS AS PREDICTORS OF NEUROLOGICAL OUTCOME
磁共振参数作为神经系统结果的预测因子
批准号：
6308613
负责人：
ANTHONY JAMES BARKOVICH
金额：
$2.58万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-12-01 至 2000-11-30
来源：
https://reporter.nih.gov/project-details/6308613
关键词：
bioimaging /biomedical imaging cerebral ischemia /hypoxia cerebrovascular imaging /visualization clinical research glutamates human subject magnetic resonance imaging newborn human (0-6 weeks) prognosis

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This study will test the hypothesis that cerebral perfusion abnormalities and evidence of blood-brain barrier breakdown on MRI will correlate with standard clinical definitions of perinatal asphyxia. Furthermore, MRI findings of altered cerebral perfusion or impaired blood-brain barrier in specific regions of the brain can predict the subset of infants who succumb from hypoxic-ischemic encephalopathy or those who survive with significant neurodevelopmental sequelae on follow-up neurological evaluation.
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