JACKSON HEART STUDY--TRAINING CENTER

杰克逊心脏研究中心--培训中心

• 批准号: 6405923
• 负责人: ASOKA S SRINIVASAN
• 金额: --
• 依托单位: TOUGALOO COLLEGE
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-06-01 至 2005-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6405923
• 关键词: African American; cardiovascular disorder education; cardiovascular disorder epidemiology; cardiovascular disorder prevention; clinical research; community; coronary disorder; disease /disorder etiology; geographic site; heart enlargement; heart failure; human middle age (35-64); human old age (65+); human subject; hypertension; kidney circulation disorder; longitudinal human study; minority health professional; minority institution research support; stroke

Despite encouraging declines over the past three decades, cardiovascular disease (CVD) remains the number one cause of death in the U.S. A number of risk factors for coronary heart disease (CHD) and stroke have been identified; however, relatively few population-based studies have examined CVD in a large group of African-Americans. Existing evidence indicated that death rates in Mississippi are the highest in the nation and particularly high among African-Americans. Between 1980 and 1995, the decline in CVD death rates has been the slowest among African-American men and women in Mississippi relative to other groups in the state and nation. The Jackson Heart Study (JHS) is a single-site prospective epidemiologic investigation of CVD among approximately 6,500 African-Americans ages 35 to 84, from Jackson, Mississippi metropolitan area. The primary objective of the JHS is to investigate the causes of CVD in African- Americans to learn how to best prevent this group of diseases in the future. More specific objectives include: (1) Identifying factors which influence the development and worsening of CVD in African-Americans, with an emphasis on Manifestations related to high blood pressure (such as enlargement of the left ventricle of the heart, coronary artery disease, heart failure, stroke and disorders affecting the blood vessels of the kidney). (2) Building research capabilities in minority institutions at the undergraduate and graduate level by developing partnerships between minority and majority institutions and enhancing participation of minority investigators in large-scale epidemiologic studies. (3) Attaching minority students to and preparing them for careers in public health and epidemiology. This project serves as the Coordinating Center where all data collected during the study will be managed, analysis of the data will be performed, and community involvement will be coordinated.

尽管在过去的三十年里，心血管疾病（CVD）的死亡率出现了令人鼓舞的下降，但它仍然是美国的头号死亡原因。然而，相对较少的基于人群的研究在非洲裔美国人的大群体中检查了心血管疾病。现有证据表明，密西西比州的死亡率是全国最高的，非洲裔美国人的死亡率尤其高。1980年至1995年间，相对于该州和全国其他群体，密西西比州非裔美国男女心血管疾病死亡率的下降速度是最慢的。杰克逊心脏研究（JHS）是一项针对大约6500名年龄在35岁至84岁之间的非裔美国人的心血管疾病的单点前瞻性流行病学调查。JHS的主要目标是调查非裔美国人心血管疾病的原因，以了解如何在未来最好地预防这类疾病。更具体的目标包括：(1)确定影响非裔美国人心血管疾病发展和恶化的因素，重点关注与高血压相关的表现（如心脏左心室增大、冠状动脉疾病、心力衰竭、中风和影响肾脏血管的疾病）。(2)通过发展少数民族院校和多数民族院校之间的伙伴关系，加强少数民族研究者对大规模流行病学研究的参与，建设少数民族院校本科和研究生水平的研究能力。(3)培养少数民族学生从事公共卫生和流行病学工作。该项目将作为协调中心，对研究期间收集的所有数据进行管理，对数据进行分析，并协调社区参与。