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AUGMENTATION THERAPY FOR CONGENITAL ALPHA1 PROTEINASE INHIBITOR THERAPY

AUGMENTATION THERAPY FOR CONGENITAL ALPHA1 PROTEINASE INHIBITOR THERAPY
先天性 ALPHA1 蛋白酶抑制剂治疗的强化治疗
批准号：
6425985
负责人：
EDWARD J CAMPBELL
金额：
$0.16万
依托单位：
UNIVERSITY OF UTAH
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6425985
关键词：
alpha 1 antitrypsin clinical research drug adverse effect drug screening /evaluation elastin human subject pharmacokinetics radiography respiratory function serology /serodiagnosis urinalysis

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中文摘要
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英文摘要
This is a multicenter, category D study designed to test to the efficacy and safety of a new (1-antitrypsin preparation. The Utah site has recruited five subjects, and all of them were evaluated. All participants will continue to receive 60 mg/kg/week of the new preparation for up to two years. Bronchoalveolar lavages were performed on all subjects at enrollment (to establish baseline values), and again a week after the sixth infusion of (1-PI or control product. Data analyses are currently being done by the industrial sponsor. No reports are yet available, although the drug does appear to be safe.
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AUGMENTATION THERAPY--CONGENITAL ALPHA1 PROTEINASE INHIB
  • 批准号：
    6304934
  • 项目类别：
  • 资助金额：
    $0.16万
  • 财政年份：
    1999
  • 负责人：
    EDWARD J CAMPBELL
  • 依托单位：
    UNIVERSITY OF UTAH
AUGMENTATION THERAPY FOR CONGENITAL ALPHA1 PROTEINASE INHIBITOR THERPAY
  • 批准号：
    6114862
  • 项目类别：
  • 资助金额：
    $2.81万
  • 财政年份：
    1998
  • 负责人：
    EDWARD J CAMPBELL
  • 依托单位：
    UNIVERSITY OF UTAH
AUGMENTATION THERAPY FOR CONGENITAL ALPHA1 PROTEINASE INHIBITOR THERAPY
  • 批准号：
    6218455
  • 项目类别：
  • 资助金额：
    $0.16万
  • 财政年份：
    1998
  • 负责人：
    EDWARD J CAMPBELL
  • 依托单位：
    UNIVERSITY OF UTAH
PREVALENCE OF ALPHA 1 ANTITRYPSIN DEFICIENCY IN ASTHMA
  • 批准号：
    6245915
  • 项目类别：
  • 资助金额：
    $2.15万
  • 财政年份：
    1997
  • 负责人：
    EDWARD J CAMPBELL
  • 依托单位：
    UNIVERSITY OF UTAH
海外基金