PREDNISONE & FISH OIL SUPPLEMENTS IN CHILDREN & YOUNG ADULTS W/ IGA NEPHROLOGY

伊加肾病是一种肾脏疾病，它导致尿液中的血液和蛋白质流失，甚至在儿童时期开始时也会导致严重的肾衰竭。 不幸的是，伊加肾病没有经过证实的治疗方法，尽管有一些报告描述了用鱼油补充剂或泼尼松药物成功治疗这种疾病的患者。参加者将被要求参加一项为期5年的临床试验，该试验将比较每隔一天的泼尼松或每日鱼油胶囊与安慰剂（一种不含药物的药丸）治疗我的伊加肾病。 本研究的目的是评估鱼油补充剂或隔日泼尼松是否可以预防或减缓儿童，青少年和年轻成人中重度伊加肾病患者的肾功能下降。 医生和病人都不会被告知他们正在接受三种治疗中的哪一种。

IgA nephropathy is a disease of the kidneys which leads to loss of blood and protein in the urine and can lead to severe kidney failure even when it begins in childhood. Unfortunately, there is no proven treatment for IgA nephropathy, although a few reports have described the successful treatment of patients with this condition with either fish oil supplements or a medication called prednisone. Those taking part will be asked to participate in a 5-year clinical trial which will compare every-other-day prednisone or daily fish oil capsules with a placebo (a pill which contains no medicine) in the treatment of my IgA nephropathy. The purpose of this study to be the evaluation of whether fish oil supplements or alternate-day prednisone can prevent or slow the decline in kidney function expected in children, adolescents and young adults with moderate to severe IgA nephropathy. Neither the doctor or patient will be told which one of the three treatments they are taking.