PREDNISONE & FISH OIL SUPPLEMENTS IN CHILDREN & YOUNG ADULTS W/ IGA NEPHROLOGY

IGA肾病是一种肾脏疾病，会导致血液和尿液中蛋白质的流失，甚至在儿童时期就会导致严重的肾衰竭。不幸的是，目前还没有得到证实的治疗IgA肾病的方法，尽管有一些报告描述了用鱼油补充剂或一种名为强的松的药物成功地治疗这种疾病的患者。这些参与者将被要求参加一项为期5年的临床试验，将每隔一天服用强的松或每日服用鱼油胶囊与安慰剂(一种不含药物的药片)在治疗我的IgA肾病方面进行比较。这项研究的目的是评估鱼油补充剂或隔日强的松是否可以预防或减缓患有中到重度IgA肾病的儿童、青少年和年轻人预期的肾功能下降。医生和患者都不会被告知他们正在接受三种治疗中的哪一种。

IgA nephropathy is a disease of the kidneys which leads to loss of blood and protein in the urine and can lead to severe kidney failure even when it begins in childhood. Unfortunately, there is no proven treatment for IgA nephropathy, although a few reports have described the successful treatment of patients with this condition with either fish oil supplements or a medication called prednisone. Those taking part will be asked to participate in a 5-year clinical trial which will compare every-other-day prednisone or daily fish oil capsules with a placebo (a pill which contains no medicine) in the treatment of my IgA nephropathy. The purpose of this study to be the evaluation of whether fish oil supplements or alternate-day prednisone can prevent or slow the decline in kidney function expected in children, adolescents and young adults with moderate to severe IgA nephropathy. Neither the doctor or patient will be told which one of the three treatments they are taking.