Effect of a four-food elimination diet in children with eosinophilic oesophagitis – a multi-centre, randomised controlled trial and investigation of disease mechanisms

四食物消除饮食对嗜酸粒细胞性食管炎患儿的影响——多中心、随机对照试验及疾病机制研究

• 批准号: nhmrc : 1029972
• 负责人: A/Pr Bircan Erbas
• 金额: $ 35.93万
• 依托单位: Murdoch Childrens Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/effect-four-food-disease-mechanisms/110724
• 关键词: Effect; four; food; elimination; diet

Eosinophilic oesophagitis (EO) is a recently recognised form of allergic inflammation in the oesophagus. EO is increasingly common in childhood and often linked to food allergy. Its treatment in children mainly relies on complex elimination diets or a liquid elemental formula which may require tube feeding due to poor taste. This Australian multi-centre trial will assess the effects of a four-food elimination diet in children with EO and will investigate novel disease mechanisms.

嗜酸性食管炎（EO）是最近认识到的食管过敏性炎症。EO在儿童时期越来越常见，通常与食物过敏有关。其在儿童中的治疗主要依赖于复杂的消除饮食或液体元素配方，由于味道差，可能需要管饲。这项澳大利亚多中心试验将评估四种食物消除饮食对EO儿童的影响，并将研究新的疾病机制。