PROBING ELASTICITY WITH THE ATOMIC FORCE MICROSCOPE
PROBING ELASTICITY WITH THE ATOMIC FORCE MICROSCOPE
批准号:
6413460
负责人:
EMILIOS K DIMITRIADIS
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
中文摘要
原子力显微镜(AFM)正日益成为在微观尺度上测量材料性能的一线工具。然而,当涉及到软生物材料如细胞时,广泛使用的测量方法和数据分析方法都发现了严重的问题。在这里,我们开发了一种改进的实验方法,并开发了收集的AFM分析的理论框架
英文摘要
The atomic force microscope (AFM) is increasingly becoming a first line tool for measuring material properties at microscopic scales. When it comes to soft biological materials such as cells, however, serious problems have been identified with both the widely used measuring approach and with the data analysis methods. Here we develop an improved experimental approach and develop the theoretical framework for the analysis of collected AFM
force-displacement data. We also establish the applicability domain for both the experimental and theoretical frameworks. The results of the project are being verified by extracting elastic moduli for soft gels using the AFM and then comparing those results with those obtained from macroscopic measurements.
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Elastic Properties Of The Tectorial Membrane
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批准号:6548679
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:EMILIOS K DIMITRIADIS
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依托单位:
Probing The Elasticity Of Biological Samples With The At
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批准号:6837008
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:EMILIOS K DIMITRIADIS
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依托单位:
Magnetic Resonance Elastography
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批准号:6837026
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:EMILIOS K DIMITRIADIS
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Problems in Coclear Micromechanics
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资助金额:$0.0万
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财政年份:--
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Studies on the Nature of the Centromeric Nucleosome
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批准号:8556169
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资助金额:$4.8万
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Interactions among GalR-binding sites on bacterial DNA
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Kinetics of Protein Absorption on Lipid Bilayers
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负责人:EMILIOS K DIMITRIADIS
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依托单位:
Atomic Force Microscopy Imaging of Protein/DNA Complexes
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批准号:7013049
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:EMILIOS K DIMITRIADIS
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依托单位:
Problems in Coclear Micromechanics
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批准号:7734360
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Scanning Probe Microscopy for the Intramural Research Community
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项目类别:
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资助金额:$535.87万
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财政年份:--
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负责人:EMILIOS K DIMITRIADIS
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依托单位:
Problems in Coclear Micromechanics
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批准号:7593818
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项目类别:
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资助金额:$0.98万
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财政年份:--
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负责人:EMILIOS K DIMITRIADIS
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依托单位:
Mapping Elastic Properties of Complex Biological Tissue
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批准号:7593838
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项目类别:
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资助金额:$0.51万
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财政年份:--
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负责人:EMILIOS K DIMITRIADIS
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依托单位:
Problems in Coclear Micromechanics
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批准号:7146060
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:EMILIOS K DIMITRIADIS
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依托单位:
Molecular Interactions Involved In Gal Repression
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批准号:6548704
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:EMILIOS K DIMITRIADIS
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依托单位:
Kinetics of Protein Absorption on Lipid Bilayers; Atomic
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批准号:7013047
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:EMILIOS K DIMITRIADIS
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Structural Studies of Novel DNA Vectors for Non-viral Gene Transfer
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项目类别:
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资助金额:$4.18万
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财政年份:--
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负责人:EMILIOS K DIMITRIADIS
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依托单位:
Mapping Elastic Properties of Complex Biological Tissue
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批准号:7967896
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项目类别:
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资助金额:$0.44万
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财政年份:--
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负责人:EMILIOS K DIMITRIADIS
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Studies of Retinoschisin 1 on the membrane of retinal cell inner segments
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批准号:7967915
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资助金额:$1.46万
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财政年份:--
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负责人:EMILIOS K DIMITRIADIS
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依托单位:
Mapping Elastic Properties of Complex Biological Tissue
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项目类别:
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资助金额:$0.0万
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财政年份:--
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Problems in Cochlear Micromechanics
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项目类别:
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资助金额:$2.03万
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财政年份:--
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负责人:EMILIOS K DIMITRIADIS
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依托单位: