课题基金 / 基金详情

PROBING ELASTICITY WITH THE ATOMIC FORCE MICROSCOPE

PROBING ELASTICITY WITH THE ATOMIC FORCE MICROSCOPE
用原子力显微镜探测弹性
批准号:
6413460
负责人:
EMILIOS K DIMITRIADIS
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:

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相关文献

中文摘要
翻译
原子力显微镜(AFM)正日益成为在微观尺度上测量材料性能的一线工具。然而,当涉及到软生物材料如细胞时,广泛使用的测量方法和数据分析方法都发现了严重的问题。在这里,我们开发了一种改进的实验方法,并开发了收集的AFM分析的理论框架
英文摘要
The atomic force microscope (AFM) is increasingly becoming a first line tool for measuring material properties at microscopic scales. When it comes to soft biological materials such as cells, however, serious problems have been identified with both the widely used measuring approach and with the data analysis methods. Here we develop an improved experimental approach and develop the theoretical framework for the analysis of collected AFM force-displacement data. We also establish the applicability domain for both the experimental and theoretical frameworks. The results of the project are being verified by extracting elastic moduli for soft gels using the AFM and then comparing those results with those obtained from macroscopic measurements.
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会议论文
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