Ultrafast Spectroscopic Studies DNA Nanostructures for All Optical Voltage Sensing

对跨膜或神经元内的电压或电位的全光学电压传感是理解生物物理学中一系列问题的重要工具。然而，传统的电压敏感染料需要几个人才能对电位的变化做出反应。在这个项目中，我们将超快光谱的能力与基于DNA折纸的人工纳米结构相结合，开发出具有亚pS响应和亚10 meV电压灵敏度的新一代电压传感器。

All optical voltage sensing of voltage or potentials across membranes or in neurons is an important tool for understanding a range of problems in biophysics. However, traditional voltage sensitive dyes take can take several us to react to changes in potential. In this project we combine the power of ultrafast spectroscopy with artificial nanostructures based on DNA origami, to develop a new generation of voltage sensors with sub-ps response and sub 10meV voltage sensitivity.