Developing a Robust Youth Depression Prevention Program

制定强有力的青少年抑郁症预防计划

• 批准号: 6539244
• 负责人: JOHN RICHARD WEISZ
• 金额: $ 14.27万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-05-07 至 2004-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6539244
• 关键词: adolescence (12-20); child mental health service; clinical research; cognitive behavior therapy; depression; education evaluation /planning; group counseling; human subject; mental disorder prevention; middle childhood (6-11); training

DESCRIPTION: (adapted from Investigator's abstract) Depressive disorders are among the most common mental health concerns for adolescents and are associated with serious and enduring functional impairments. Although mounting evidence indicates that prevention of depressive disorders is possible, research-supported programs are not widely available to at risk youth. A primary barrier to program dissemination has been the need for a level of leader training and supervision that cannot be sustained outside the context of a research program. The goal of this collaborative study between UCLA and the United Behavioral Health managed care company is to develop and test a robust youth depression prevention program intended for use in real-world settings. The video-guided Primary and Secondary Control Enhancement Training (PASCET) Preventive Intervention is a cognitive-behavioral group intervention designed for reliable implementation with minimal group leader training. This proposal is a response to PA-99-1 34: Exploratory/Development Grants for MH Intervention Research. The project consists of two phases designed to set the stage for a subsequent large-scale effectiveness trial. Program development work in Phase 1 will include video production and use of focus groups to improve the clarity and appeal of the intervention. Feedback from youth aged 10-14 will be used to create a final version of the video, leader's manual and participant workbook. Assessment of the intervention effect in Phase 2 will include pilot testing procedures for training group leaders and assessment of leader adherence to protocol. Participants will be 160 children of depressed parents, aged 10-14, selected due to their elevated biological, psychological, and social risk for depression. In keeping with the goal of real-world sustainability, group leaders will be clinicians on the UBH provider panel, not members of the research team. Pilot implementation of the intervention will include estimation of intervention effect size to determine the sample size required for a full test of the program and preliminary identification of potential intervention mediators and moderators.

描述：（改编自研究者摘要）抑郁症是 青少年最常见的心理健康问题之一， 患有严重且持久的功能障碍。尽管越来越多的证据 表明预防抑郁症是可能的， 研究支持的方案没有广泛提供给风险青年。一 计划传播的主要障碍是需要一定程度的 领导者的培训和监督，不能持续的背景下， 一个研究项目加州大学洛杉矶分校和 联合行为健康管理护理公司是开发和测试一个强大的 青少年抑郁症预防计划旨在用于现实世界的设置。 视频引导的初级和次级控制增强培训（PASCET） 预防性干预是一种认知行为团体干预， 以确保可靠的实施，并尽可能少地进行组长培训。 本提案是对PA-99-1 34：以下项目的勘探/开发赠款的回应 MH干预研究。该项目包括两个阶段，旨在 为后续的大规模有效性试验奠定基础。程序开发 第一阶段的工作将包括视频制作和使用焦点小组， 提高干预的清晰度和吸引力。来自青年的反馈 10-14将用于创建最终版本的视频，领导者手册和 参与者工作簿。第二阶段的干预效果评估将 包括培训小组领导人试点测试程序， 领导人遵守协议。参与者将是160名抑郁症儿童 父母，10-14岁，由于他们的生物，心理， 和抑郁症的社会风险。为了与现实世界的目标保持一致 可持续性，小组领导人将是UBH提供者小组的临床医生，而不是 研究团队的成员。干预措施的试点实施将 包括估计干预效应量以确定样本量 需要对程序进行全面测试，并初步确定 潜在的干预调解员和主持人。