Saliva Test for Caries Risk

初步研究表明， 年轻人唾液中的成分和DFT（蛀牙和/或补牙的数量） 成年人了这种相关性和有限的个人 变异预计，非侵入性唾液测试能够预测三个 统计上显著的类别，相当于高、中、低 累积龋齿经验。目标是开发和验证一个 商业上可行的，简单的唾液测试，可以管理， 在非临床环境中进行评估，预测累积的 龋齿经验和预测未来龋齿发展的风险 年龄组这项测试将使广泛的领域筛选，以确定 最需要口腔护理的人。第一阶段目标 包括完善测试及其在年轻人中的分析， 在儿童中应用测试的条件，并开发一个原型， 商业测试此外，克服和利用 儿童特定的DFT变化和累积的龋齿经验是 建议道。第二阶段将实地测试和验证原型测试车辆 不同的年龄、种族和文化群体。第三阶段将涉及 测试和校准套件的制造和分销合作伙伴。

DESCRIPTION Preliminary studies show that there is correlation between a component in saliva and DFT (number of decayed and/or filled teeth) in young adults. The combined strength of this correlation and limited individual variation anticipate that a non-invasive saliva test is able to forecast three statistically significant categories, equivalent to high, medium, and low cumulative caries experience. The goal is to develop and validate a commercially viable, simple saliva test, which can be administered and evaluated in a non-clinical setting, which forecasts the level of accumulated caries experience and predicts the risk of future caries development for all age groups. This test will make possible broad field screening to identify individuals with the greatest immediate need for oral care. Phase I Aims include refining the test and its analysis in young adults, identifying conditions for applying the test in children, and developing a prototype for a commercial test. In addition, strategies for overcoming and capitalizing on child-specific variations of DFT and cumulative caries experience are suggested. Phase II will field test and validate the prototype test vehicle with different age, racial, and cultural groups. Phase III will involve partners for manufacture and distribution of the test and calibration kits.