Saliva Test for Caries Risk

初步研究表明， 青少年唾液成分和DFT(龋齿和/或充填牙数) 成年人。这种关联性和有限的个体的综合力量 不同的是，一种非侵入性唾液测试能够预测三种 具有统计意义的类别，相当于高、中和低 累积龋齿经验。我们的目标是开发和验证 商业上可行的，简单的唾液测试，可以管理和 在非临床环境中进行评估，它预测累积的水平 所有人的龋齿经历和未来龋齿发展的风险预测 各年龄段。这项测试将使广泛的现场筛查成为可能 最迫切需要口腔护理的人。第一阶段目标 包括改进测试及其在年轻人中的分析，确定 在儿童中应用该测试的条件，并开发一个原型 商业测试。此外，克服和利用的战略 儿童特定的DFT和累积龋齿经验的变化是 建议。第二阶段将对原型测试车进行现场测试和验证 有不同的年龄、种族和文化群体。第三阶段将涉及 制造和分销测试和校准套件的合作伙伴。

DESCRIPTION Preliminary studies show that there is correlation between a component in saliva and DFT (number of decayed and/or filled teeth) in young adults. The combined strength of this correlation and limited individual variation anticipate that a non-invasive saliva test is able to forecast three statistically significant categories, equivalent to high, medium, and low cumulative caries experience. The goal is to develop and validate a commercially viable, simple saliva test, which can be administered and evaluated in a non-clinical setting, which forecasts the level of accumulated caries experience and predicts the risk of future caries development for all age groups. This test will make possible broad field screening to identify individuals with the greatest immediate need for oral care. Phase I Aims include refining the test and its analysis in young adults, identifying conditions for applying the test in children, and developing a prototype for a commercial test. In addition, strategies for overcoming and capitalizing on child-specific variations of DFT and cumulative caries experience are suggested. Phase II will field test and validate the prototype test vehicle with different age, racial, and cultural groups. Phase III will involve partners for manufacture and distribution of the test and calibration kits.