MOOD MANAGEMENT VS MOOD TOLERANCE IN ALCOHOL TREATMENT

本研究项目的长期目标是对比认知行为技能训练（情绪管理- MM）和基于焦虑的治疗（情绪耐受-MT）在治疗被诊断为酒精滥用或依赖的个体中的有效性。具体目标包括：1）评估MM和MT在帮助问题饮酒者保持戒酒方面的相对功效; 3）检查情绪失调与复发之间的关系。情绪失调已成为许多酒精滥用/依赖理论中的一个突出因素，广泛使用旨在改善情绪调节的治疗模块。很少有研究评估旨在改善酒精依赖患者情绪调节的疗法的疗效，也没有研究直接比较针对消极情绪的认知行为和基于焦虑的治疗方法的疗效。本研究将招募128名清醒时间不超过3个月的受试者。将对受试者进行评估并随机分配至MM或MT组。两种治疗条件下的参与者将完成每周两次的90分钟组，共五周。预计在一周、三个月和六个月的随访评估中，两组（MM与MT）在酒精使用、情感调节和当前情感状态方面存在差异。该项目将提供试验数据，为计划于2001年提交的一级登记册申请提供信息。

The long-term objective of this research project is to contrast the effectiveness of cognitive behavioral skills training (Mood Management- MM) and exposure-based therapy (Mood Tolerance-MT) in the treatment of individuals diagnosed with alcohol abuse or dependence. Specific Aims include: 1) evaluating the relatively efficacy of MM and MT in helping problem drinkers to maintain abstinence from alcohol, and 3) to examine the relationship between mood dysregulation and relapse. Mood dysregulation has become a prominent factor in many theories of alcohol abuse/dependence with widespread use of treatment modules designed to improve mood regulation. Few studies have been conducted to evaluate the efficacy of therapies designed to improve mood regulation among alcohol dependent patients, and no studies have directly compared the efficacy of cognitive behavioral and exposure-based treatment approaches targeting negative mood. 128 participants with no more than three-months sobriety will be recruited for the present study. Participants will be assessed and randomly assigned to either MM or MT. Participants in both treatment conditions will complete twice-weekly 90 minute groups for a total of five weeks. Between group (MM vs. MT) differences in alcohol use, affective regulation, and current affective state are expected at a one- week, three-month, and six-month follow-up assessment. This project will provide pilot data to inform an RO1 application with a planned submission in the year 2001.