WIH/Brown Epidemiology/Clinical Trials Training Program

描述（申请人摘要）：WIH/布朗流行病学/临床试验培训计划的目标是为对避孕和生殖健康研究感兴趣的临床培训妇产科医生提供2-3年的流行病学，生物统计学和临床试验教育。培训方案将通过实现以下目标来实现这一目标：（1）为每位研究员提供流行病学、研究设计、统计方法、临床试验、性别问题、研究行为、科学出版、赠款写作方面的核心课程，以及成为生殖健康领域成功调查员所需的其他工具; 2）为每位研究员提供妇产科和社区卫生方面的导师;这些人将提供指导和专业知识，以确保成功的学术发展; 3）提供有利于避孕和生殖健康调查的研究基础设施和支持环境。该方案将利用布朗大学社区卫生系、妇女健康研究司和布朗大学医学院妇产科系乔治安德森成果衡量股以及国家围产期信息中心的现有优势。研究员可参与的持续研究项目包括：（避孕咨询方法预防性传播疾病和意外怀孕的随机临床试验（RCT））; 2）功能失调性子宫出血的手术治疗结果项目（STOP-DUB）- RCT; 3）妇女健康倡议- RCT和观察性研究; 4）高血压和不良妊娠结局研究（HAPO）- RCT; 5）第一和第二个三个月评估非整倍体风险（FASTER）研究- RCT。除了流行病学、生物统计学的教学课程以及性别问题和学术发展的核心研讨会外，研究员还必须完成至少一项避孕或生殖健康领域的辅导独立研究，包括流行病学研究或临床试验的设计、进行和分析。这一多学科计划将提供一个新的妇产科调查人员的干部谁将进一步在生殖健康的科学数据库。

DESCRIPTION (Applicant's Abstract): The goal of the WIH/Brown Epidemiology/Clinical Trials Training Program is to provide a 2-3 year period of education in epidemiology, biostatistics, and clinical trials to clinically-trained obstetrician-gynecologists who are interested in contraceptive and reproductive health research. The training program will achieve this goal by accomplishing the following objectives: 1) provide each fellow with a core curriculum in epidemiology, research design, statistical methods, clinical trials, gender issues, conduct of research, scientific publishing, grant writing, and additional tools necessary to become a successful investigator in reproductive health; 2) provide each fellow with a mentor in both Obstetrics and Gynecology and Community Health; these individuals will provide the guidance and expertise to assure successful academic development; 3) provide the research infrastructure and supportive environment conducive to investigation into contraception and reproductive health. The Program will take advantage of the existing strengths of the Department of Community Health at Brown University, the Division of Research in Women's Health and the George Anderson Outcomes Measurement Unit in the Department of Obstetrics and Gynecology, Brown University School of Medicine, and the National Perinatal Information Center (NPIC). Examples of on-going research projects available to fellows include: 1) Project PROTECT (randomized clinical trial (RCT) of contraceptive counseling approaches to prevent sexually transmitted diseases and unplanned pregnancies); 2) Surgical Treatment Outcomes Project for Dysfunctional Uterine Bleeding (STOP-DUB) - RCT; 3) Women's Health Initiative - RCT and observational; 4) Hyperglycemia and Adverse Pregnancy Outcomes Study (HAPO) - RCT; 5) First and 2nd Trimester Evaluation of Risk of Aneuploidy (FASTER) Study- RCT. In addition to didactic course work in epidemiology, biostatistics, and core seminars in gender issues and academic development, fellows must also complete at least one mentored independent study in the area of contraception or reproductive health including the design, conduct and analysis of an epidemiologic study or clinical trial. This multidisciplinary program will provide a new cadre of ob/gyn investigators who will further the scientific database in reproductive health.