A GIS Based Workbench to Interpret Cancer Maps

描述(由申请者提供)：这项研究将开发和测试一个 确定乳腺癌和乳腺癌超额癌症负担区域的方法 爱荷华州的结直肠癌。它将完善地理准入的措施 爱荷华州通过计算机提供癌症预防、治疗和筛查服务 使用关于个人的精细比例地理数据的值，空间选择 个人和服务提供商的位置，它将使用爱荷华州癌症 十年期间(1900-1999)的登记(SEER)数据和相关联的患者档案 到联邦医疗保险和选定的医疗保险记录。它将计算统计数据 Logistic回归模型家族中的模型，以关联特定的 癌症负担指标可预测反映当地特征的易挥发性物质 个人的地域和特征。癌症负担衡量标准 乳腺癌和结直肠癌处于确诊阶段，五年存活率， 和筛查的概率。该方法将制定一种地区性的 模拟工作台(RSW)以生成预期的范围和变化 基于当地数据的爱荷华州小地理区域癌症负担测算 该地区的人口统计特征和全州的癌症负担率。 随机变化将使用蒙特卡罗模拟方法进行计算。 将使用修改后的地理要素提取来识别区域 方法：研究方法。该方法将在爱荷华州进行验证，并在第三年进行计划 将被开发用于在另外两个州采用和实施它 隶属于北美癌症协会的强大癌症登记 注册处。结果可用于规划更适当的癌症预防和 控制程序。研究人员是专门从事地理研究的地理学家 信息科学、医学地理学和流行病学家 在癌症发病率、预防和控制方面的大量研究记录。

DESCRIPTION (provided by applicant): This research will develop and test a methodology for identifying regions of excess cancer burden for breast and colorectal cancer in Iowa. It will refine measures of geographic access to cancer prevention, treatment, and screening services in Iowa by computing values using fine-scaled geographic data on individuals, the spatial choices of individuals, and the locations of services providers, It will use Iowa Cancer Registry (SEER) data for a ten year period (1900-1999) and linked patient files to Medicare and selected medical insurance records. It will compute statistical models from the family of logistic regression models to associate specific cancer burden measures to predictor vanables that capture local characteristics of the area and characteristics of the individuals. The cancer burden measures for breast and colorectal cancer are stage at diagnosis, five-year survival, and probability of screening. The methodology will develop a regional simulation workbench (RSW) to generate the expected range and variations in the cancer burden measures for small geographic areas of Iowa based on local demographic characteristics of the area and statewide cancer burden rates. Stochastic variations will be computed using Monte Carlo simulation methods. Regions will be identified using modified, geographic feature extraction methods. The methodology will be validated in Iowa and, in year three, plans will be developed for its adoption and implementation in two other states with strong cancer registries belonging to the North American Association of Cancer Registries. Results can be used to plan more appropriate cancer prevention and control programs. The researchers are geographers who specialize in geographic information science and medical geography and epidemiologists with a substantial record of research in cancer incidence, prevention and control.