Making inference to the population from nationally representative longitudinal surveys with missing data due to nonresponse to biological data collect
从全国代表性的纵向调查中推断人口,由于对收集的生物数据没有答复而导致数据缺失
基本信息
- 批准号:1911760
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:英国
- 项目类别:Studentship
- 财政年份:2017
- 资助国家:英国
- 起止时间:2017 至 无数据
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
Large-scale surveys provide extremely important sources of data for research into a wide variety of key social issues. This is especially the case where the people selected to participate are part of a sample that is representative of the population and also where the survey is repeated at regular intervals for the same sample over time. Some such surveys also include a health data component where body measurements and biological samples are collected in addition to the survey questionnaire. This has created new and exciting possibilities for research into the interactions between social phenomena (such as values and behaviours), economic indicators (such as income) and markers of physical health (such as blood pressure and cholesterol levels). A research area currently of particular interest involves measuring the physical markers of stress in order to investigate the potential social correlates and causes. Related to this is the concept of allostatic load which represents the physiological consequences of repeated or chronic stress and has been linked to socio-economic status (SES) and poor health outcomes. Biological survey data has the potential to give important insights and contribute to the understanding of the causes and effects of allostatic load levels when analysed over time with associated social and economic data.However, this exciting research potential also brings new methodological challenges. Whilst survey samples can be selected to represent the general population, not everyone agrees or is able to participate. The extra steps required to collect biological data, in particular blood samples, can add to this inability and/or reluctance to respond positively to the survey request. This may lead to biases in the results of statistical analyses if these are generalised to the population as a whole without adequate compensation for the data that are missing. An example would be if those in the selected sample with certain health conditions were less likely to provide blood samples. Results obtained from using only the collected blood data to analyse the associations between SES and markers of chronic stress would not represent the whole sample, leading to potentially incorrect conclusions about the population.The aim of this project is to address these challenges by developing and clarifying the appropriate methods to deal with missing biological data in surveys in order to make inference to the general population, particularly in reference to estimating the relationship between allostatic load and SES. This is both from the viewpoint of actions that can be taken before and during the fieldwork carried out to collect the data and also the analysis that takes place once the data are made available to researchers. The work focuses not only on evaluating and comparing existing missing data techniques but also on incorporating new forms of auxiliary data that can be collected during the survey process and investigating how these can be used to improve the robustness of current methods. In particular, this includes using additional information about the trained nurses that carry out data collection in the field, such as their sample allocation and experience. The auxiliary data also includes records taken by nurses during the process of contacting and gaining cooperation from sample members, such as the number and length of call attempts to a household. The data for the project come from two large-scale surveys in the UK that include biological data collection:UKHLS and ELSA. UKHLS is an annual general population survey in the UK with a sample of 40,000 households at wave 1. Waves 2 and 3 were conducted during 2009-13 and included a nurse visit for subsamples of eligible respondents. ELSA is a survey of the older population in England and is carried out every two years. The sample at wave 1 included 11,500 respondents aged at least 50 in 2002. Nurse visits have been conducted every two years from wave 2 onwards
大规模调查为研究各种关键的社会问题提供了极其重要的数据来源。特别是在被选择参加的人是代表人口的样本的情况下,而且随着时间的推移,对同一样本定期重复进行调查。一些此类调查还包括健康数据部分,除调查问卷外,还收集人体尺寸和生物样本。这为研究社会现象(如价值观和行为)、经济指标(如收入)和身体健康指标(如血压和胆固醇水平)之间的相互作用创造了新的令人兴奋的可能性。目前特别感兴趣的一个研究领域涉及测量压力的物理标记,以调查潜在的社会相关因素和原因。与此相关的是不平衡负荷的概念,它代表反复或慢性应激的生理后果,并与社会经济状况(SES)和糟糕的健康结果有关。随着时间的推移,结合相关的社会和经济数据进行分析,生物调查数据有可能提供重要的见解,并有助于理解平衡负荷水平的原因和影响。然而,这种令人兴奋的研究潜力也带来了新的方法挑战。虽然可以选择调查样本来代表一般人群,但并不是每个人都同意或能够参与。收集生物数据,特别是血液样本所需的额外步骤可能会增加对调查请求作出积极回应的能力和/或不情愿。这可能会导致统计分析结果的偏差,如果统计分析结果被推广到整个人口,而没有对缺失的数据进行适当的补偿。一个例子是,在选定的样本中,有某些健康状况的人提供血液样本的可能性较小。仅使用收集的血液数据分析SES和慢性应激标志物之间的联系所获得的结果不能代表整个样本,导致关于人口的潜在错误结论。本项目的目的是通过开发和澄清适当的方法来处理调查中丢失的生物数据来应对这些挑战,以便对一般人群做出推断,特别是在估计不平衡负荷和SES之间的关系方面。这既是从收集数据的实地工作之前和进行期间可以采取的行动的角度,也是从一旦向研究人员提供数据后进行的分析的角度来看的。这项工作不仅侧重于评估和比较现有的缺失数据技术,而且还侧重于纳入可在调查过程中收集的新形式的辅助数据,并调查如何利用这些数据来改进现有方法的稳健性。特别是,这包括使用关于在外地进行数据收集的训练有素的护士的额外信息,例如他们的样本分配和经验。辅助数据还包括护士在接触和获得样本成员合作的过程中记录的记录,如尝试呼叫家庭的次数和时长。该项目的数据来自英国的两项大规模调查,其中包括生物数据收集:UKHLS和ELSA。UKHLS是英国的一项年度人口普查,在第一波调查中抽样调查了4万户家庭。第二波和第三波调查是在2009-13年间进行的,其中包括对符合条件的受访者的亚样本进行护士访问。ELSA是一项针对英格兰老年人口的调查,每两年进行一次。第一波的样本包括11,500名在2002年年龄在50岁以上的受访者。从第二次浪潮开始,每两年进行一次护士探视
项目成果
期刊论文数量(2)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Interviewer Effects from a Total Survey Error Perspective
从总体调查错误的角度来看访调员的影响
- DOI:10.1201/9781003020219-21
- 发表时间:2020
- 期刊:
- 影响因子:0
- 作者:Pashazadeh F
- 通讯作者:Pashazadeh F
Advances in Longitudinal Survey Methodology
纵向调查方法的进展
- DOI:10.1002/9781119376965.ch5
- 发表时间:2021
- 期刊:
- 影响因子:0
- 作者:Pashazadeh F
- 通讯作者:Pashazadeh F
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其他文献
吉治仁志 他: "トランスジェニックマウスによるTIMP-1の線維化促進機序"最新医学. 55. 1781-1787 (2000)
Hitoshi Yoshiji 等:“转基因小鼠中 TIMP-1 的促纤维化机制”现代医学 55. 1781-1787 (2000)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
LiDAR Implementations for Autonomous Vehicle Applications
- DOI:
- 发表时间:
2021 - 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
吉治仁志 他: "イラスト医学&サイエンスシリーズ血管の分子医学"羊土社(渋谷正史編). 125 (2000)
Hitoshi Yoshiji 等人:“血管医学与科学系列分子医学图解”Yodosha(涉谷正志编辑)125(2000)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
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Effect of manidipine hydrochloride,a calcium antagonist,on isoproterenol-induced left ventricular hypertrophy: "Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,K.,Teragaki,M.,Iwao,H.and Yoshikawa,J." Jpn Circ J. 62(1). 47-52 (1998)
钙拮抗剂盐酸马尼地平对异丙肾上腺素引起的左心室肥厚的影响:“Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,
- DOI:
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- 期刊:
- 影响因子:0
- 作者:
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的其他文献
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{{ truncateString('', 18)}}的其他基金
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用于实时测量循环生物标志物的植入式生物传感器微系统
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2901954 - 财政年份:2028
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2896097 - 财政年份:2027
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