CORE--TISSUE PROCUREMENT

该计划项目的组织采购核心设施将提供 为每一位研究者服务。 这将加强每个项目，增加 有效利用时间和资金，并确保 项目 核心将获得人类肿瘤组织，并维持一个库， 冰冻恶性肿瘤，邻近非恶性皮肤，非阳光暴露皮肤 和外周血淋巴细胞。 它还将维持实验室 样本编码，以维护患者机密性， 实验偏差 肿瘤细胞系也将维持在核心中， 根据需要分发给研究者。 所有样本将 组织学证实。 肿瘤对mRNA、DNA和 将通过核心设施为所有项目提供蛋白质 允许：1）一个安全的，中央储存库的基本材料， 具有准确编码记录保存能力的研究项目。 （二） 多个研究人员有效利用稀缺材料。 第三章 收集、储存和处理程序的标准化，确保 不同研究者获得的材料一致。 4)一个 高效的跟踪、交付和处理系统，可调整并满足 计划项目的组织要求。

The Tissue Procurement Core Facility for t his Program Project will provide services to each investigator. This will enhance each project, increase the efficient use of time and funds, and ensure coordination between projects. The Core will obtain human tumor tissue and maintain a bank of frozen malignant tumors, adjacent non-malignant skin, non-sun exposed skin and peripheral blood lymphocytes. It will also maintain laboratory specimen coding to maintain patient confidentiality and prevent experimental bias. Tumor cell line will also be maintained in the Core and distributed amongst investigators as required. All specimens will be histologically verified. Central processing of tumors for mRNA, DNA, and protein will be provided for all projects through the Core facility allowing: 1) a safe, central repository of essential materials for the research project s with accurate coded record keeping capabilities. 2) efficient utilization of scarce materials by multiple investigators. 3) standardization of collection, storage, and processing procedures, ensuring uniformity of materials obtained by different investigators. 4) An efficient tracking, delivery, and processing system that adjusts and meets the tissue requirements for the program project.