Developmental Research Program

发展研究计划

• 批准号: 7510717
• 负责人: GARY L CLAYMAN
• 金额: $ 9.2万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2013-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7510717
• 关键词: Area; Award; Budgets; Cancer Center; Carbon; Collaborations; Communities; Data; Dental; Development; Doctor of Medicine; Doctor of Philosophy; Extramural Activities; Fluorescent Dyes; Fostering; Funding; Goals; Grant; Head; Head and Neck Cancer; Image; Incidence; Institutes; Investigation; Lead; Malignant - descriptor; Methods; Minority; Nanotechnology; Neck; Numbers; Oral; Patients; Peer Review; Pilot Projects; Premalignant; Process; Program Research Project Grants; Puerto Rico; Qualifying; Quality of life; Rate; Reproduction spores; Research; Research Personnel; Research Project Grants; Research Proposals; Rice; Texas; Tobacco; Translational Research; Universities; University of Texas M D Anderson Cancer Center; Woman; base; career; craniofacial; falls; improved; innovation; malignant mouth neoplasm; mortality; nanoparticle; novel; oncology; outreach; programs; response

A major goal of this SPORE and, more specifically, this program is to identify and fund projects that will lead to clinically testable hypotheses aimed at reducing the incidence and mortality rate of head and neck cancer or improving the quality of life of patients with head and neck cancers. The DRP has continued to support new, novel research in head and neck cancer, with 12 DRP awards made to talented investigators (Mitchell Frederick, Ph.D., Ann Marie Gillenwater, M.D., Michael Story, Ph.D., Ho-Young Lee, Ph.D., Julie Izzo, M.D., Vassiliki A. Papadimitrakopoulou, M.D., Mahitosh Mandel, Ph.D., K.S. Clifford Chao, M.D., Pulivarthi Rao, Ph.D., Gianpietro Dotti, M.D., Nadarajah Vigneswaran, D.M.D., and Waldemar Priebe, Ph.D., over the past 4 years. In addition, 12 DRP proposals were submitted in response to the Fall 2006 solicitation, which were recently reviewed and, with input of our Internal Advisors and Executive Committee, will allow funding of three additional awards to Faye M. Johnson, M.D., Ph.D., Ja Seok Koo, Ph.D., in early 2007, and a subsequent award to an investigator from Rice University, Rebecca Kortum-Richards, Ph.D. The specific objectives of the Developmental Research Program are to: 1. Solicit pilot projects in head and neck cancer translational research that have significant potential for reducing the incidence and mortality rate of head and neck cancer and/or improving the quality of life of patients with head and neck cancers. 2. Foster collaborative efforts among SPORE investigators and with other investigators to encourage the development of new and innovative ideas and approaches. 3. Encourage and assist young investigators with promising preliminary data developed with support of this Program to apply for extramural peer-reviewed funding. 4. When necessary or possible, promote the most promising projects in the Developmental Research Program to full SPORE research projects. The projects funded through the Developmental Research Program are diverse but share common themes related to their translational potential in head and neck cancers. In response to our previous review, we have revised and clarified the process by which applications are solicited from qualified candidates, and have initiated a new collaboration, based on an institutional U54 grant ("Partnership for Excellence"), with the Puerto Rico Cancer Center at the University of Puerto Rico to enhance our outreach in soliciting novel developmental projects from qualified candidates, particularly women and minority investigators. We believe these and other changes to our application will significantly strengthen this program over the next grant cycle.

这个项目的一个主要目标，更具体地说，这个项目是确定和资助将导致 旨在降低头颈癌发病率和死亡率的临床可验证假说 或者提高头颈癌患者的生活质量。民主同盟党继续支持 头颈部癌症的新的、新颖的研究，12个DRP奖授予有才华的调查人员(米切尔) Frederick，Ph.，Ann Marie Gillenwater，M.D.，Michael Story，Ph.D.，Ho-Young Lee，Ph.D.，Julie Izzo，M.D. 首页--期刊主要分类--期刊细介绍--期刊题录与文摘--期刊详细文摘内容 博士，Gianpietro Dotti，M.D.，Nadarajah Vigneswaran，D.M.D.，Waldemar Priebe，Ph.D. 好几年了。此外，为响应2006年秋季的征集，提交了12份发展方案提案，它们是 最近进行了审查，并在我们的内部顾问和执行委员会的参与下，将允许为 2007年初，向Faye M.Johnson，M.D.，Ph.D.，Ja Seok Koo，Ph.D.颁发了另外三个奖项，以及一个 随后授予莱斯大学研究员丽贝卡·科尔图姆-理查兹博士。 发展研究方案的目标是： 1.征集有重大潜力的头颈癌转化研究试点项目 降低头颈癌的发病率和死亡率和/或提高患者的生活质量 头颈部癌症患者。 2.促进孢子调查人员之间以及与其他调查人员的合作努力，以鼓励 发展新的和创新的想法和方法。 3.鼓励和协助年轻的调查人员提供有希望的初步数据，以支持这一点 申请校外同行评审资助的计划。 4.在必要或可能的情况下，推动发展研究中最有前途的项目 计划进行充分的孢子研究项目。 通过发展研究计划资助的项目多种多样，但有共同的主题 与它们在头颈部癌症中的翻译潜力有关。为了回应我们之前的审查，我们已经 修订和澄清了向合格候选人征集申请的程序，并已 在机构U54赠款(“卓越伙伴关系”)的基础上，与 波多黎各大学波多黎各癌症中心加强我们在征集小说方面的外展 来自合格候选人，特别是妇女和少数群体调查员的发展项目。我们相信 这些和对我们应用程序的其他更改将在下一次拨款中显著加强该计划 周而复始。