Comprehending and modelling the workings of the animal brain

理解和模拟动物大脑的运作

• 批准号: FT140100452
• 负责人: Prof Andrew Barron
• 金额: $ 47.6万
• 依托单位: Macquarie University
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-06-01 至 2022-11-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT140100452
• 关键词: Comprehending; modelling; workings; animal; brain

Truly understanding how the brain operates is a grand challenge of 21st century neuroscience. Progress toward this goal can be made through studying small-brained animals, like the honey bee. This project aims to use microscopy and pharmacology to analyse the neural mechanisms by which bees learn and classify complex things. This will enable the construction of a computational model of decision making in the bee brain. Analysing this model will test what is understood about the operation of the animal brain, and what simulates it. This project aims to reveal how neural circuits make complex decisions; establish key principles and foundational studies for comprehending larger more complex brains, and yield new approaches to machine learning.

真正了解大脑如何运作是 21 世纪神经科学的巨大挑战。通过研究蜜蜂等小脑动物，可以在实现这一目标方面取得进展。该项目旨在利用显微镜和药理学来分析蜜蜂学习和分类复杂事物的神经机制。这将使蜜蜂大脑中决策的计算模型的构建成为可能。分析该模型将测试对动物大脑运作的理解以及模拟它的内容。该项目旨在揭示神经回路如何做出复杂的决策；建立理解更大更复杂的大脑的关键原则和基础研究，并产生新的机器学习方法。