GROWTH FACTOR CONTROL OF APOPTOSIS DURING PLACENTATION
GROWTH FACTOR CONTROL OF APOPTOSIS DURING PLACENTATION
批准号:
6520910
负责人:
Sohaib A. Khan
金额:
$22.16万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1994
资助国家:
美国
项目状态:
已结题
起止时间:
1994-04-01 至 2004-03-31
关键词:
BCL2 gene /protein apoptosis cathepsin D cell differentiation cell growth regulation cell line confocal scanning microscopy cysteine endopeptidases cytochrome c decidua embryo implantation endometrium estrogens gene expression growth factor receptors hormone regulation /control mechanism immunoelectron microscopy immunoprecipitation in situ hybridization laboratory rat progesterone receptor binding transforming growth factors western blottings yeast two hybrid system
中文摘要
点击翻译按钮获取中文摘要
英文摘要
DESCRIPTION: (Adapted from applicant's abstract) The studies proposed
in this application will: (1) determine if progesterone withdrawal at
different stages of decidualization would affect the expression of bcl-2
gene family members; this information will be correlated with DNA
fragmentation in the decidual cells; (2) investigate why induced Bax
expression failed to cause death of decidual cells by determining if Bax
activity is compromised by Bcl-xL or hsp-25; (3) determine the
expression of TGF-beta and apoptotic mediators (cathepsin-D, cytochrome-
c, apaf-1, and caspase-3) in the GG-AD decidual cell line, and assess
the consequence of overexpressing bax or inhibiting bax and cathepsin-D
in GG-AD cells.
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会议论文
Nuclear Receptors and Endocrine Disorders
-
批准号:6727778
-
项目类别:
-
资助金额:$1.9万
-
财政年份:2004
-
负责人:Sohaib A. Khan
-
依托单位:
BIACORE 2000 SYSTEM
-
批准号:2766820
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项目类别:
-
资助金额:$23.8万
-
财政年份:1999
-
负责人:Sohaib A. Khan
-
依托单位:
ESTROGEN RECEPTOR VARIANTS AND BREAST CANCER
-
批准号:2443308
-
项目类别:
-
资助金额:$16.17万
-
财政年份:1996
-
负责人:Sohaib A. Khan
-
依托单位:
ESTROGEN RECEPTOR VARIANTS AND BREAST CANCER
-
批准号:2895702
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项目类别:
-
资助金额:$17.49万
-
财政年份:1996
-
负责人:Sohaib A. Khan
-
依托单位:
Estrogen Receptor Variants and Breast Cancer
-
批准号:6479205
-
项目类别:
-
资助金额:$27.54万
-
财政年份:1996
-
负责人:Sohaib A. Khan
-
依托单位:
Estrogen Receptor Variants and Breast Cancer
-
批准号:6625819
-
项目类别:
-
资助金额:$27.54万
-
财政年份:1996
-
负责人:Sohaib A. Khan
-
依托单位:
ESTROGEN RECEPTOR VARIANTS AND BREAST CANCER
-
批准号:2733288
-
项目类别:
-
资助金额:$16.82万
-
财政年份:1996
-
负责人:Sohaib A. Khan
-
依托单位:
Estrogen Receptor Variants and Breast Cancer
-
批准号:7048684
-
项目类别:
-
资助金额:$26.89万
-
财政年份:1996
-
负责人:Sohaib A. Khan
-
依托单位:
Estrogen Receptor Variants and Breast Cancer
-
批准号:6745608
-
项目类别:
-
资助金额:$27.54万
-
财政年份:1996
-
负责人:Sohaib A. Khan
-
依托单位:
Estrogen Receptor Variants and Breast Cancer
-
批准号:6870190
-
项目类别:
-
资助金额:$27.54万
-
财政年份:1996
-
负责人:Sohaib A. Khan
-
依托单位:
ESTROGEN RECEPTOR VARIANTS AND BREAST CANCER
-
批准号:2115515
-
项目类别:
-
资助金额:$16.94万
-
财政年份:1996
-
负责人:Sohaib A. Khan
-
依托单位:
GROWTH FACTOR CONTROL OF APOPTOSIS DURING PLACENTATION
-
批准号:6387610
-
项目类别:
-
资助金额:$21.51万
-
财政年份:1994
-
负责人:Sohaib A. Khan
-
依托单位:
GROWTH FACTOR CONTROL OF APOPTOSIS DURING PLACENTATION
-
批准号:2202160
-
项目类别:
-
资助金额:$15.63万
-
财政年份:1994
-
负责人:Sohaib A. Khan
-
依托单位:
GROWTH FACTOR CONTROL OF APOPTOSIS DURING PLACENTATION
-
批准号:6182050
-
项目类别:
-
资助金额:$20.89万
-
财政年份:1994
-
负责人:Sohaib A. Khan
-
依托单位:
GROWTH FACTOR CONTROL OF APOPTOSIS DURING PLACENTATION
-
批准号:2860827
-
项目类别:
-
资助金额:$22.05万
-
财政年份:1994
-
负责人:Sohaib A. Khan
-
依托单位:
GROWTH FACTOR CONTROL OF APOPTOSIS DURING PLACENTATION
-
批准号:6636869
-
项目类别:
-
资助金额:$22.82万
-
财政年份:1994
-
负责人:Sohaib A. Khan
-
依托单位:
Regulation of Cellular Growth and Differentiation
-
批准号:7123544
-
项目类别:
-
资助金额:$27.95万
-
财政年份:1993
-
负责人:Sohaib A. Khan
-
依托单位:
Regulation of Cellular Growth and Differentiation
-
批准号:7481043
-
项目类别:
-
资助金额:$14.38万
-
财政年份:1993
-
负责人:Sohaib A. Khan
-
依托单位:
Regulation of Cellular Growth and Differentiation
-
批准号:7800641
-
项目类别:
-
资助金额:$5.19万
-
财政年份:1993
-
负责人:Sohaib A. Khan
-
依托单位:
REGULATION OF CELLULAR GROWTH AND DIFFERENTIATION
-
批准号:6171947
-
项目类别:
-
资助金额:$18.48万
-
财政年份:1993
-
负责人:Sohaib A. Khan
-
依托单位:
国内基金
海外基金
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