Regulation of Cellular Growth and Differentiation

细胞生长和分化的调节

基本信息

  • 批准号:
    7123544
  • 负责人:
  • 金额:
    $ 27.95万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    1993
  • 资助国家:
    美国
  • 起止时间:
    1993-08-01 至 2011-04-30
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): This application is a competitive renewal for a training grant entitled "Regulation of cellular growth and differentiation", originally funded in 1993. The goal of this grant proposal remains unchanged, that is to provide solid training to pre- and postdoctoral trainees in contemporary cancer biology, so that they can pursue independent careers in this discipline. A group of 19 investigators with clear focus in cancer research are seeking funds to train 4 predoctoral and 4 postdoctoral fellows through this program. The preceptors are derived from seven departments of the. These include the Department of Cell Biology, Department of Environmental Health, Department of Developmental Biology, Department of Internal Medicine, Department of Molecular Genetics, Department of Genome Sciences, and Department of Molecular and Cellular Physiology. All of the training faculty members are well funded by NIH and other funding agencies, such as American Cancer Society and DOD Breast Cancer Program. Research supports of a majority of the training faculty come from National Cancer Institute. As detailed in the body of this proposal, active collaborations exist among the training grant faculty. With the strong backing of the Medical Center Administration, the cancer program has seen a remarkable growth in the past five years with new recruitments at the center. This has benefited the training grant and has improved our efforts to recruit trainees of higher caliber. Efforts to recruit the best trainees, including minority candidates will continue. Entering predoctoral candidates have undergraduate bachelor's degree in biological, chemical or physical sciences. Postdoctoral candidates must have a Ph.D., M.D., or D.V.M. and proven academic excellence. A well-defined training program, with new training approaches, is outlined for pre- and postdoctoral trainees that include mandatory participation in a course on Biology of Cancer, Cancer Journal Club, Cancer Seminar Series, "Awareness to Cancer Patient Care", Scientific Writing and Annual Retreat. The evaluation of the program and the progress of the trainees will be periodically reviewed by the Advisory and the Executive Committees. Past trainees of this program have gone on to careers in cancer research at excellent institutions. We are committed to produce well-trained researchers, who conform to the criteria for cancer research training envisioned by the NCI.
描述(由申请人提供):本申请是对题为“细胞生长和分化的调节”的培训补助金的竞争性更新,最初资助于1993年。本资助计划的目标保持不变,即为当代癌症生物学的pre- and -博士后学员提供坚实的培训,使他们能够在这一学科中独立发展。一个由19名明确专注于癌症研究的研究人员组成的小组正在寻求资金,通过该计划培养4名博士生和4名博士后。这些导师来自于大学的七个部门。其中包括细胞生物学系、环境卫生学系、发育生物学系、内科学系、分子遗传学学系、基因组科学系、分子和细胞生理学学系。所有的培训教员都是由NIH和其他资助机构,如美国癌症协会和国防部乳腺癌项目资助的。大部分培训教员的研究支持来自国家癌症研究所。如本提案正文所述,培训资助教员之间存在积极的合作。在医疗中心管理局的大力支持下,癌症项目在过去五年中有了显著的增长,中心招募了新员工。这使培训补助金受益,并使我们更努力地招聘更高水平的受训人员。将继续努力招收包括少数民族候选人在内的最优秀的学员。进入博士预科的候选人具有生物、化学或物理科学学士学位。博士后候选人必须具有博士学位,医学博士或D.V.M.,并证明学术卓越。一个明确的培训计划和新的培训方法,为pre- phd和post - phd学员概述,包括强制性参加癌症生物学课程,癌症杂志俱乐部,癌症系列研讨会,“癌症患者护理意识”,科学写作和年度务静会。咨询委员会和执行委员会将定期审查该方案的评价和受训人员的进展情况。该项目过去的学员已经在优秀的机构从事癌症研究工作。我们致力于培养训练有素的研究人员,他们符合NCI所设想的癌症研究培训标准。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Sohaib A. Khan其他文献

Estrogen receptor variants ERΔ5 and ERΔ7 down-regulate wild-type estrogen receptor activity
雌激素受体变体 ERΔ5 和 ERΔ7 下调野生型雌激素受体活性
Progesterone withdrawal and RU-486 treatment stimulate apoptosis in specific uterine decidual cells
黄体酮停药和 RU-486 治疗刺激特定子宫蜕膜细胞凋亡
  • DOI:
    10.1038/sj.cdd.4400202
  • 发表时间:
    1997
  • 期刊:
  • 影响因子:
    12.4
  • 作者:
    B. C. Moulton;J. Motz;Cleo Serdoncillo;K. Akcali;Sohaib A. Khan
  • 通讯作者:
    Sohaib A. Khan
Estrogen Receptor and Breast Cancer: A Historical Perspective
雌激素受体和乳腺癌:历史视角
Control of Apoptosis in the Uterus During Decidualization
子宫蜕膜化过程中细胞凋亡的控制
  • DOI:
    10.1007/978-1-4612-1944-6_5
  • 发表时间:
    1997
  • 期刊:
  • 影响因子:
    4.3
  • 作者:
    B. C. Moulton;K. Akcali;T. Ogle;T. Brown;J. Motz;Sohaib A. Khan
  • 通讯作者:
    Sohaib A. Khan
Effects of Oral Administration of Tamoxifen, Toremifene, Dehydroepiandrosterone, and Vorozole on Uterine Histomorphology in the Rat (44493)
口服他莫昔芬、托瑞米芬、脱氢表雄酮和伏罗唑对大鼠子宫组织形态学的影响 (44493)
  • DOI:
    10.1177/153537020022300311
  • 发表时间:
    2000
  • 期刊:
  • 影响因子:
    3.2
  • 作者:
    K. Nephew;E. Osborne;R. Lubet;C. Grubbs;Sohaib A. Khan
  • 通讯作者:
    Sohaib A. Khan

Sohaib A. Khan的其他文献

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{{ truncateString('Sohaib A. Khan', 18)}}的其他基金

Nuclear Receptors and Endocrine Disorders
核受体和内分泌失调
  • 批准号:
    6727778
  • 财政年份:
    2004
  • 资助金额:
    $ 27.95万
  • 项目类别:
BIACORE 2000 SYSTEM
BIACORE 2000 系统
  • 批准号:
    2766820
  • 财政年份:
    1999
  • 资助金额:
    $ 27.95万
  • 项目类别:
ESTROGEN RECEPTOR VARIANTS AND BREAST CANCER
雌激素受体变异体与乳腺癌
  • 批准号:
    2443308
  • 财政年份:
    1996
  • 资助金额:
    $ 27.95万
  • 项目类别:
ESTROGEN RECEPTOR VARIANTS AND BREAST CANCER
雌激素受体变异体与乳腺癌
  • 批准号:
    2895702
  • 财政年份:
    1996
  • 资助金额:
    $ 27.95万
  • 项目类别:
Estrogen Receptor Variants and Breast Cancer
雌激素受体变异与乳腺癌
  • 批准号:
    6479205
  • 财政年份:
    1996
  • 资助金额:
    $ 27.95万
  • 项目类别:
Estrogen Receptor Variants and Breast Cancer
雌激素受体变异与乳腺癌
  • 批准号:
    6625819
  • 财政年份:
    1996
  • 资助金额:
    $ 27.95万
  • 项目类别:
ESTROGEN RECEPTOR VARIANTS AND BREAST CANCER
雌激素受体变异体与乳腺癌
  • 批准号:
    2733288
  • 财政年份:
    1996
  • 资助金额:
    $ 27.95万
  • 项目类别:
Estrogen Receptor Variants and Breast Cancer
雌激素受体变异与乳腺癌
  • 批准号:
    7048684
  • 财政年份:
    1996
  • 资助金额:
    $ 27.95万
  • 项目类别:
Estrogen Receptor Variants and Breast Cancer
雌激素受体变异与乳腺癌
  • 批准号:
    6745608
  • 财政年份:
    1996
  • 资助金额:
    $ 27.95万
  • 项目类别:
ESTROGEN RECEPTOR VARIANTS AND BREAST CANCER
雌激素受体变异体与乳腺癌
  • 批准号:
    2115515
  • 财政年份:
    1996
  • 资助金额:
    $ 27.95万
  • 项目类别:

相似国自然基金

Cellular & Molecular Immunology
  • 批准号:
    30824806
  • 批准年份:
    2008
  • 资助金额:
    20.0 万元
  • 项目类别:
    专项基金项目

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