SCORE Program at New Mexico State Univ., Las Cruces

新墨西哥州立大学拉斯克鲁塞斯分校 SCORE 项目

• 批准号: 6317082
• 负责人: GLENN D KUEHN
• 金额: $ 66.67万
• 依托单位: NEW MEXICO STATE UNIVERSITY LAS CRUCES
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-09-09 至 2004-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6317082
• 关键词: minority institution research support

This is an application for a new SCORE Program at New Mexico State University (NMSU) at Las Cruces. A goal of NMSU is to expand research is at the institution for participation by ethnic minority students who desire to pursue careers in the biomedical science disciplines. The proposed SCORE Program has its goals: (i) To significantly improve the capabilities of NMSU to conduct biomedically relevant research by increasing the numbers of faculty who conduct biomedical research, increasing the inventory of specialized single-user research instrumentation, and improving the capacity to maintain research instrumentation; (ii) To significantly improve the quantity and quality of biomedical research conducted at NMSU by broadening grantsmanship efforts of faculty participants and increasing the numbers and quality of research publications; (iii) To integrate the activities of the SCORE Program with an anticipated RISE Program to maximize resources for training minority scientists in the biomedical sciences by engaging students in SCORE Program research projects; (iv) To increase the capacity of NMSU to self-evaluate, assess, and monitor its multi- component research programs by engaging trained personnel in the SCORE Program's evaluation plan and subjecting the Program to annual review by an external evaluation committee. This application contains research proposals for nineteen research subprojects and three pilot subprojects. Disciplines represented among these proposals include Agronomy, Animal Science, Anthropology, Biochemistry, Biology, Chemistry, Chemical Engineering, Molecular Biology, Microbiology and Psychology. The research topics of proposed projects include methods for radiolabeling medical diagnostic reagents with technetium and rhenium, avian cardiovascular adaptations, the bacterial proteosome, glycosylation processes in CHO cells, apoptosis, acid tolerance of E. coli O157:h7, metabolic engineering of secondary metabolism, evolution of RNA viruses, cytosolic and chloroplastic glutamine synthase, biological dechlorination reactions, mechanisms of environmental stress resistance, toxicokinetics of swainonine, neuromodulation of growth hormone, maternal/infant synchrony in cortisol and behavior development, embryonic control of blood pressure, modification of clays for resolving racemic mixtures, gene expressions during inner ear development, and chemical synthesis of cation chelators, steroids and etoposide derivatives, and boronated biomolecules. This SCORE Program will continue a 24-year old MBRS Program which has advanced 280 minority students (83% of participants) on to post baccalaureate programs and produced 52 minority Ph.D. recipients since 1974.

这是拉斯克鲁塞斯的新墨西哥州州立大学（NMSU）的新SCORE项目申请表。NMSU的一个目标是扩大研究是在该机构的参与，由少数民族学生谁愿意追求职业生涯中的生物医学科学学科。拟议的SCORE计划有其目标：（一）通过增加进行生物医学研究的教师人数，增加专门的单用户研究仪器的库存，并提高维护研究仪器的能力，以显着提高NMSU进行生物医学相关研究的能力; ㈡通过扩大教员参与者的研究努力和增加研究出版物的数量和质量，大大提高在国立医学大学进行的生物医学研究的数量和质量;（iii）将SCORE计划的活动与预期的RISE计划整合起来，通过让学生参与SCORE计划研究项目，最大限度地利用资源来培训生物医学科学领域的少数族裔科学家;（四）提高国家管理支助股自我评价、评估并监测其多个，通过在SCORE计划的评估计划中聘请训练有素的人员，并由外部评估委员会对该计划进行年度审查，来评估组成研究计划。本申请包含十九个研究子项目和三个试点子项目的研究建议。这些建议中的学科包括农学、动物科学、人类学、生物化学、生物学、化学、化学工程、分子生物学、微生物学和心理学。拟开展的研究课题包括医用诊断试剂的锝、锝标记方法、禽类心血管适应性、细菌蛋白体、CHO细胞糖基化过程、细胞凋亡、大肠杆菌耐酸性等。大肠杆菌O 157：h7，次级代谢的代谢工程，RNA病毒的进化，胞质和叶绿体谷氨酰胺合酶，生物脱氯反应，环境应激抗性机制，苦马豆素的毒代动力学，生长激素的神经调节，皮质醇和行为发育中的母婴同步，血压的胚胎控制，用于分解外消旋混合物的粘土的修饰，内耳发育期间的基因表达，以及阳离子螯合剂、类固醇和依托泊苷衍生物和硼化生物分子的化学合成。该SCORE计划将延续已有24年历史的MBRS计划，该计划已将280名少数民族学生（占参与者的83%）推进到学士后课程，并产生了52名少数民族博士学位。自1974年以来，