Core--Research development

核心--研究开发

• 批准号: 6468882
• 负责人: PAUL D COLEMAN
• 金额: $ 13万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-07-01 至 2002-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6468882
• 关键词: aging; biomedical facility; health science research support

The proposed Nathan Shock Center on Aging as a four-fold purpose: (1) To enhance the quality of research in the basic biology of aging, (2) to facilitate coordination of research on aging, (3) to create a regional/national resource and (4) to create an environment for faculty growth in aging research. The creation of an environment for faculty growth by the Research Development Core also will enhance the quality of research in the basic biology of aging. The creation of an environment for faculty growth by the Research Development Core also will enhance the quality of research in the basic biology of aging. A major focus of the Research Development will be to promote the integration of the technologies offered by the Core so to develop research in the cellular and molecular basis of cell senescence and death in selected model systems. Research programs utilizing the Cores will be able to discover aging- related genes, localize their gene products, describe their phenotype and determine the function of the gene products. This integration will be created by a series of activities: (1) Rigorous selection of applications for the support of Pilot Projects, (2) rigorous selection of faculty with approved Pilot Projects for limited salary support, (3) a formal program of mentoring junior faculty and others new to th4e biology of aging by senior faculty (4) creation of a seminar course in the biology of aging and (5) mounting a program of guest speakers and retreats for prevention of findings on the biology of aging. The selection of applications for support of Pilot Projects and the selection of faculty for limited salary support will be by a committee of senior faculty. All these activities are designed to create an interactive and collegial but rigorous environment in which the intellectual ferment would lead to recruitment of new faculty to research in the cell and molecular biology of aging and provide them with outstanding facilities to support the production of high quality research by outstanding faculty.

拟议中的内森·休克老龄化中心有四个目的：（1）提高老龄化基础生物学研究的质量，（2）促进老龄化研究的协调，（3）创建区域/国家资源，（4）为老龄化研究的教师成长创造环境。研究发展核心为教师成长创造环境也将提高衰老基础生物学研究的质量。研究发展核心为教师成长创造环境也将提高衰老基础生物学研究的质量。研究开发的一个主要重点是促进核心提供的技术的整合，以便在选定的模型系统中开展细胞衰老和死亡的细胞和分子基础研究。利用核心的研究计划将能够发现衰老相关基因，定位其基因产物，描述其表型并确定基因产物的功能。这一整合将通过一系列活动实现：（1）严格选择支持试点项目的申请，（2）严格选择具有批准的试点项目的教师，以获得有限的工资支持，（3）由资深教师指导初级教师和其他新接触衰老生物学的人的正式计划（4）创建衰老生物学研讨会课程和（5）举办一个特邀演讲者和务虚会的计划，以预防衰老生物学的发现。申请支持试点项目的选择和教师的选择有限的工资支持将由一个委员会的高级教师。所有这些活动的目的是创造一个互动和合议，但严格的环境中，智力发酵将导致招聘新的教师在衰老的细胞和分子生物学的研究，并为他们提供优秀的设施，以支持优秀的教师生产高质量的研究。