TRAINING FUTURE GENERATIONS OF MENTAL HEALTH RESEARCHERS

这个R25应用程序是围绕两个整体主题组织-基础和临床研究之间的桥梁和科学和临床服务之间的桥梁。 我们计划进一步发展所需的基础设施，在转化和公共卫生模式的框架内进行临床研究培训。 我们计划的一个关键前提是神经科学，神经影像学和遗传学之间建立联系的重要性，以及它们在整个生命周期中对精神和身体疾病干预的应用。 我们还计划在我们建立的对照临床试验中进行治疗结果研究的传统与NIMH目前优先考虑的干预研究之间建立桥梁。 我们的具体目标包括：（1）制定一项初级教师学者计划，为我们的研究教育和培训中心（RETC）执行委员会竞争性选择的教师提供两年25%的工资支持。 短期目标是促进这些教师的K奖职业发展应用程序的发展;长期目标是确保他们作为独立的研究者进行临床研究的成功;（2）开发具有两个轨道的课程，一个用于转化研究，第二个用于干预研究。这两个方向将包括在学年内举办一个小型课程（10节课）和两个密集的夏季工作坊（各一周）;（3）为初级学院学者的试点研究提供四个奖项，收集初步数据以支持他们的K奖申请;以及（4）雇用一名全职统计员，为初级学院学者提供支持。 解决了有关招聘代表性不足的少数民族和妇女的问题，并提出了评估方案成功与否的具体标准（例如，还介绍了获得资助的早期职业发展奖和职业中期面向病人的研究奖的增加情况。

This R25 application is organized around two overall themes-building bridges between basic and clinical research and building bridges between science and clinical service. We plan to develop further the infrastructure needed to conduct clinical research training within the frameworks of both translational and public health models. A key premise of our program is the importance of forging links between neuroscience, neuroimaging, and genetics and their applications to interventions with psychiatric and physical illnesses throughout the lifespan. We also plan to build bridges between the tradition we have established of treatment outcome research done in controlled clinical trials and the current priority accorded by NIMH to intervention research with an increased public health orientation. Our specific aims include: (1) development of a Junior Faculty Scholars Program that will provide 25 percent salary support for two years to faculty members selected competitively by the Executive Committee of our Research Education and Training Center (RETC). The short-term goal is to facilitate the development of K-award career development applications by these faculty; the long-term goal is to ensure their success as independent investigators doing clinical research; (2) development of a curriculum with two tracks-one for translational research and a second for intervention research. Both tracks will involve one mini-course during the academic year (10 sessions) and two intensive summer workshops (one week each); (3) provision of four awards for pilot research studies by Junior Faculty Scholars collecting initial data in support of their K-award applications; and (4) hiring of one full-time statistician who will provide support to the Junior Faculty Scholars. Issues regarding recruitment of underrepresented minorities and women are addressed, and specific criteria for evaluating the success of the program (e.g., an increase in funded early career development awards and mid-career patient-oriented research awards) are also described.