Effects of replacement and withdrawal of testosterone in human males on muscle, bone and fat

人类男性睾酮替代和撤除对肌肉、骨骼和脂肪的影响

• 批准号: nhmrc : 1017233
• 负责人: Dr Ada Cheung
• 金额: $ 10.45万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/effects-replacement-withdrawal-bone-fat/109840
• 关键词: Effects; replacement; withdrawal; testosterone; human

Male sex hormone or androgen deficiency (AD) is a common, but under-diagnosed condition. AD decreases well being and contributes to muscle weakness, bone fragility and weight gain. Cutting edge technology will be used to help explain how AD may relate to these negative effects, particularly on muscle function. Given the importance of aging, frailty, osteoporosis and obesity, understanding the role of hormones in these conditions may have major implications for prevention and treatment.

男性性激素或雄激素缺乏(AD)是一种常见但被低估的疾病。AD会降低幸福感，并导致肌肉无力、骨骼脆弱和体重增加。尖端技术将被用来帮助解释AD如何与这些负面影响相关，特别是对肌肉功能的影响。鉴于衰老、虚弱、骨质疏松症和肥胖的重要性，了解激素在这些疾病中的作用可能对预防和治疗具有重要意义。