Enhanced Power for Assisted Blood Circulation

描述（由申请人提供）：全人工心脏（TAH）和相关器械（例如，心室辅助装置）正在出现，其为患者提供了几乎无限的患者移动性和接近正常的生活方式的潜力。正在开发的新设备是完全可植入的，独立的（电池是外部的），电力驱动系统。然而，新设备的功率和能量密度要求很高，在许多情况下超过了当今最好的电池技术。该计划的研究旨在开发能量密度为现有原电池三倍的新型原电池。在第一阶段，我们将展示增强型电池组件的可行性，并获得主要电池制造商的参与。在第二阶段，我们将把增强型电池组件集成到原型电池中，并展示与传统电池相比的性能改进。在第一阶段，我们将展示增强电池组件的可行性以及实验室电池的增强性能。在第二阶段，我们将把增强型电池组件集成到原型电池中，并在现场测试中证明与对照组相比性能有所改善。I期和II期项目将通过我们最近增加的商业电池合作伙伴和商业血泵专家得到加强。

DESCRIPTION (provided by applicant): Total Artificial Heart (TAH) and related devices (e.g., ventricular assist device) are emerging that provide the potential for almost unlimited patient mobility and near-normal lifestyle for the patient. The new devices being developed are totally implantable, self-contained (battery is external), electrically driven systems. However, the power and energy density requirements of the new devices are high and in many cases exceed the best battery technology available today. The proposed research in this program seeks to develop novel primary batteries with three times the energy density of existing primary batteries. In Phase I we will demonstrate feasibility of enhanced battery components and obtain participation of major battery manufacturer. In Phase II we will integrate enhanced battery components into prototype battery and demonstrate improved performance compared to conventional batteries. In Phase I we will demonstrate feasibility of enhanced battery components as well as enhanced performance of laboratory batteries. In Phase II we will integrate enhanced battery components into prototype batteries and in field tests demonstrate improved performance compared to controls. Both phase I and Phase II programs will be enhanced by our recent addition of both commercial battery partner and commercial blood pump expert.