CORE--MOLECULAR BIOLOGY AND GENE TRANSFECTION

核心--分子生物学与基因转染

• 批准号: 6564705
• 负责人: JEFFREY R MORGAN
• 金额: $ 20.41万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-12-01 至 2002-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6564705
• 关键词: Retroviridae; biomedical facility; fibroblasts; genetic transduction; keratinocyte; plasmids; recombinant DNA; transfection /expression vector

Description: This core designs, constructs, and grows large quantities of and purifies retroviral-based vectors for use by various projects in the program. For this renewal, this core will also experiment with new enhancers/promoters in the same basic Maloney virus-based backbone and will test new lentivirus based vectors for transduction of non-dividing cells.

描述：该核心设计，构造和生长大量的和 纯化逆转录病毒载体，供项目中的各种项目使用。 为了这次更新，该核心还将试验新的增强子/启动子 在相同的基础马洛尼病毒为基础的骨干，并将测试新的慢病毒， 用于转导非分裂细胞的基于载体。