Removal of Endocrine Disruptor Bisphenol A from Water

从水中去除内分泌干扰物双酚 A

基本信息

  • 批准号:
    1942255
  • 负责人:
  • 金额:
    --
  • 依托单位:
  • 依托单位国家:
    英国
  • 项目类别:
    Studentship
  • 财政年份:
    2017
  • 资助国家:
    英国
  • 起止时间:
    2017 至 无数据
  • 项目状态:
    已结题

项目摘要

Bisphenol A (BPA) is a compound used primarily in the manufacture of polycarbonate plastics and epoxy resins. Thecompound has been confirmed as an endocrine disruptor chemical & is an environmental pollutant; ubiquitousacross aquatic environments.Whilst many health risks from acute or chronic exposure remain unknown, BPA has been shown to cause hormoneimbalances and reduce or prevent fertility in humans & several aquatic species. Recently, an EU ban on BPAbased thermal paper (used for printed cashiers' receipts) was announced and will be enforced from 2020. As BPA ison the candidate list for 'substances of very high concern', it is expected that further legislation limiting its use will beintroduced in the near future.Development of sustainable methods to control BPA concentrations, across aquatic environments, is important tomaintain the sustainability of eco-systems, and for control of water quality. This will continue to be important for theforeseeable future as BPA leeches out of waste in landfill (where ground water management is not tightly controlled)and from plastic pollution in oceans and freshwater.Current BPA removal processes are predominantly based on freshwater treatment and are very energy intensive,cost intensive, and/or demonstrate low removal efficiencies.This project aims to create a floating device which can remove BPA from water, at low energy cost, and without theneed for disruption to existing water processing infrastructure. Based on previous results, we believe it is possible todevelop, test, and optimise a sustainable BPA removal device within the scope of a PhD project. Within this project,there is also the possibility to adjust the process to remove toxic analogues of BPA - which are often used asreplacements in 'BPA free' plastics.Potential applications for this device include treatment of sea water in areas of concentrated plastic waste (such asocean gyres), at coastal waste water discharge points, and freshwa ter treatment in reservoirs.This research project relies on collaboration with Electronic and Electrical Engineering for device construction,Chemical Engineering for bio-degradation analysis, and works on different areas within Chemistry (electrochemistryand analytical methods). The work will fall into four key areas; electrochemical optimisation, development ofanalytical methods, processes for the degradation of polymerised BPA, and construction of an operational BPAremoval device.Electrochemical Process:This will involve testing the electrochemical conditions and electrode materials used in the removal process.Optimisation of the removal process will also be necessary for different sample conditions; BPA concentration,presence of radical scavengers, 'real water' samples, and samples from different environments.Analytical Methods:Analytical methods will be important for accurate quantification of BPA levels and removal efficiencies. Additionalmethods for analysis will be needed to determine by-product formation, for polymer characterization, and toxicity/estrogenic activity assessment. Significant analytical method development will be required to assess levels ofalternative pollutants.Degradation:Following removal of BPA by polymer formation, methods for degrading the polymer can be considered to regeneratethe electrode material. These methods could include UV treatment, electrochemical reductive desorption, orbiological degradation processes using bacterial colonies within microbial fuel cells.Device Construction:Removal of BPA from the environment will require functional floating devices which can carry out the electrochemicalprocess. Design, construction, testing, and optimisation of these devices will be part of the project once successfulremoval processes are established. The system will be designed to include a renewable power source, to increasethe sustainability and self-sufficiency of the process.
双酚A (BPA)是一种主要用于制造聚碳酸酯塑料和环氧树脂的化合物。该化合物已被确认为内分泌干扰物,是一种环境污染物;在水生环境中无处不在。虽然急性或慢性暴露的许多健康风险尚不清楚,但BPA已被证明会导致激素失衡,降低或阻止人类和一些水生物种的生育能力。最近,欧盟宣布禁止使用基于bpaba的热敏纸(用于打印收银员收据),并将从2020年开始实施。由于双酚a被列入“高度关注物质”候选名单,预计在不久的将来会出台进一步的立法来限制其使用。发展可持续的方法来控制双酚a在水生环境中的浓度,对于维持生态系统的可持续性和控制水质非常重要。在可预见的未来,BPA将继续从垃圾填埋场(地下水管理不严格的地方)和海洋和淡水中的塑料污染中提取,这将继续发挥重要作用。目前的双酚a去除工艺主要基于淡水处理,非常耗能、成本高,而且/或去除效率低。该项目旨在创造一种漂浮装置,可以以低能源成本从水中去除BPA,并且不需要破坏现有的水处理基础设施。基于之前的结果,我们相信在博士项目范围内开发、测试和优化可持续的双酚a去除装置是可能的。在这个项目中,也有可能调整工艺以去除BPA的有毒类似物,这些类似物通常被用作“无BPA”塑料的替代品。该装置的潜在应用包括在塑料废物集中地区(如海洋环流)处理海水,在沿海废水排放点处理海水,以及在水库处理淡水。该研究项目依赖于与电子和电气工程的合作,用于设备构建,化学工程用于生物降解分析,并在化学(电化学和分析方法)的不同领域开展工作。这项工作将分为四个关键领域;电化学优化,分析方法的发展,聚合双酚a降解的过程,以及可操作的双酚a移动装置的构建。电化学过程:这将包括测试去除过程中使用的电化学条件和电极材料。对于不同的样品条件,优化去除过程也是必要的;BPA浓度,自由基清除剂的存在,“真正的水”样本,以及来自不同环境的样本。分析方法:分析方法对于准确定量BPA水平和去除效率非常重要。需要其他的分析方法来确定副产物形成、聚合物表征和毒性/雌激素活性评估。需要开发重要的分析方法来评估替代污染物的水平。降解:通过聚合物形成去除双酚a后,可以考虑降解聚合物的方法来再生电极材料。这些方法可能包括紫外线处理、电化学还原解吸或利用微生物燃料电池中的细菌菌落进行生物降解过程。设备结构:从环境中去除双酚a将需要能够执行电化学过程的功能性浮动设备。一旦成功建立移除流程,这些设备的设计、建造、测试和优化将成为项目的一部分。该系统将被设计为包括可再生能源,以增加该过程的可持续性和自给自足。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

其他文献

吉治仁志 他: "トランスジェニックマウスによるTIMP-1の線維化促進機序"最新医学. 55. 1781-1787 (2000)
Hitoshi Yoshiji 等:“转基因小鼠中 TIMP-1 的促纤维化机制”现代医学 55. 1781-1787 (2000)。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
LiDAR Implementations for Autonomous Vehicle Applications
  • DOI:
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
生命分子工学・海洋生命工学研究室
生物分子工程/海洋生物技术实验室
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
吉治仁志 他: "イラスト医学&サイエンスシリーズ血管の分子医学"羊土社(渋谷正史編). 125 (2000)
Hitoshi Yoshiji 等人:“血管医学与科学系列分子医学图解”Yodosha(涉谷正志编辑)125(2000)。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
Effect of manidipine hydrochloride,a calcium antagonist,on isoproterenol-induced left ventricular hypertrophy: "Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,K.,Teragaki,M.,Iwao,H.and Yoshikawa,J." Jpn Circ J. 62(1). 47-52 (1998)
钙拮抗剂盐酸马尼地平对异丙肾上腺素引起的左心室肥厚的影响:“Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:

的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('', 18)}}的其他基金

An implantable biosensor microsystem for real-time measurement of circulating biomarkers
用于实时测量循环生物标志物的植入式生物传感器微系统
  • 批准号:
    2901954
  • 财政年份:
    2028
  • 资助金额:
    --
  • 项目类别:
    Studentship
Exploiting the polysaccharide breakdown capacity of the human gut microbiome to develop environmentally sustainable dishwashing solutions
利用人类肠道微生物群的多糖分解能力来开发环境可持续的洗碗解决方案
  • 批准号:
    2896097
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
A Robot that Swims Through Granular Materials
可以在颗粒材料中游动的机器人
  • 批准号:
    2780268
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
Likelihood and impact of severe space weather events on the resilience of nuclear power and safeguards monitoring.
严重空间天气事件对核电和保障监督的恢复力的可能性和影响。
  • 批准号:
    2908918
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
Proton, alpha and gamma irradiation assisted stress corrosion cracking: understanding the fuel-stainless steel interface
质子、α 和 γ 辐照辅助应力腐蚀开裂:了解燃料-不锈钢界面
  • 批准号:
    2908693
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
Field Assisted Sintering of Nuclear Fuel Simulants
核燃料模拟物的现场辅助烧结
  • 批准号:
    2908917
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
Assessment of new fatigue capable titanium alloys for aerospace applications
评估用于航空航天应用的新型抗疲劳钛合金
  • 批准号:
    2879438
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
Developing a 3D printed skin model using a Dextran - Collagen hydrogel to analyse the cellular and epigenetic effects of interleukin-17 inhibitors in
使用右旋糖酐-胶原蛋白水凝胶开发 3D 打印皮肤模型,以分析白细胞介素 17 抑制剂的细胞和表观遗传效应
  • 批准号:
    2890513
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
CDT year 1 so TBC in Oct 2024
CDT 第 1 年,预计 2024 年 10 月
  • 批准号:
    2879865
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
Understanding the interplay between the gut microbiome, behavior and urbanisation in wild birds
了解野生鸟类肠道微生物组、行为和城市化之间的相互作用
  • 批准号:
    2876993
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship

相似海外基金

Correction of endocrine disruptor-induced transgenerational epimutations by CRISPR-dCas9
通过 CRISPR-dCas9 纠正内分泌干扰物诱导的跨代表突变
  • 批准号:
    9894194
  • 财政年份:
    2019
  • 资助金额:
    --
  • 项目类别:
Production of Daphnia for endocrine disruptor sensing
用于内分泌干扰物传感的水蚤生产
  • 批准号:
    17H01880
  • 财政年份:
    2017
  • 资助金额:
    --
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Developmental consequences of prenatal exposure to endocrine disruptor chemicals - An investigation of epigenetic mechanisms in the Duisburg Birth Cohort Study
产前接触内分泌干扰物化学物质的发育后果 - 杜伊斯堡出生队列研究中表观遗传机制的调查
  • 批准号:
    353803853
  • 财政年份:
    2017
  • 资助金额:
    --
  • 项目类别:
    Research Grants
A Longitudinal Study of Endocrine Disruptor Mixtures and Reproductive Aging
内分泌干​​扰物混合物与生殖衰老的纵向研究
  • 批准号:
    9731469
  • 财政年份:
    2016
  • 资助金额:
    --
  • 项目类别:
A Longitudinal Study of Endocrine Disruptor Mixtures and Reproductive Aging
内分泌干​​扰物混合物与生殖衰老的纵向研究
  • 批准号:
    10088443
  • 财政年份:
    2016
  • 资助金额:
    --
  • 项目类别:
A Longitudinal Study of Endocrine Disruptor Mixtures and Reproductive Aging
内分泌干​​扰物混合物与生殖衰老的纵向研究
  • 批准号:
    9321364
  • 财政年份:
    2016
  • 资助金额:
    --
  • 项目类别:
Exploration of Cadmium as an Endocrine Disruptor in Prostate Cancer Disparities
镉作为内分泌干扰物在前列腺癌差异中的探索
  • 批准号:
    8875692
  • 财政年份:
    2014
  • 资助金额:
    --
  • 项目类别:
Effects of endocrine disruptor mixtures on testicular function
内分泌干​​扰物混合物对睾丸功能的影响
  • 批准号:
    464335-2014
  • 财政年份:
    2014
  • 资助金额:
    --
  • 项目类别:
    University Undergraduate Student Research Awards
Exploration of Cadmium as an Endocrine Disruptor in Prostate Cancer Disparities
镉作为内分泌干扰物在前列腺癌差异中的探索
  • 批准号:
    8754792
  • 财政年份:
    2014
  • 资助金额:
    --
  • 项目类别:
Chromatin Dynamics of Endocrine Disruptor Compounds on Estrogen Receptor Function
内分泌干​​扰物化合物对雌激素受体功能的染色质动态
  • 批准号:
    8827770
  • 财政年份:
    2013
  • 资助金额:
    --
  • 项目类别:
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了